Evidence map›Paper›PMID 29563504›Full record

ArticleNature communications2018

AUX1-mediated root hair auxin influx governs SCF

Julian Dindas, Sönke Scherzer, M Rob G Roelfsema, Katharina von Meyer, Heike M Müller, K A S Al-Rasheid, Klaus Palme, Petra Dietrich, Dirk Becker, Malcolm J Bennett and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed
34.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 215 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Mechanisms of auxin action in plant growth and development.Nature reviews. Molecular cell biology · 2025
    Review
  6. Structural basis of auxin binding and transport byProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Molecular tipping points in plant cell surface HQuantitative plant biology · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. International journal of molecular sciences · 2023
    Article
  17. Article
  18. Auxin as an architect of the pectin matrix.Journal of experimental botany · 2023
    Review
  19. Review
  20. Article

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Julian DindasInstitute for Molecular Plant Physiology and Biophysics, University of Würzburg, 97082, Würzburg, Germany.
Sönke ScherzerInstitute for Molecular Plant Physiology and Biophysics, University of Würzburg, 97082, Würzburg, Germany.
M Rob G RoelfsemaInstitute for Molecular Plant Physiology and Biophysics, University of Würzburg, 97082, Würzburg, Germany.
Katharina von MeyerInstitute for Molecular Plant Physiology and Biophysics, University of Würzburg, 97082, Würzburg, Germany.
Heike M MüllerInstitute for Molecular Plant Physiology and Biophysics, University of Würzburg, 97082, Würzburg, Germany.
K A S Al-RasheidCollege of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
Klaus PalmeInstitute of Biology II/Molecular Plant Physiology, Faculty of Biology, BIOSS Centre for Biological Signaling Studies, Centre for Biological Systems Analysis, 79104, Freiburg, Germany.
Petra DietrichMolecular Plant Physiology, Department of Biology, University of Erlangen-Nürnberg, Staudtstrasse 5, 91058, Erlangen, Germany.ORCID http://orcid.org/0000-0002-9209-8089
Dirk BeckerInstitute for Molecular Plant Physiology and Biophysics, University of Würzburg, 97082, Würzburg, Germany.
Malcolm J BennettCentre for Plant Integrative Biology, Plant & Crop Sciences, School of Biosciences, University of Nottingham, Nottingham, LE12 3RD, UK.ORCID http://orcid.org/0000-0003-0475-390X
Rainer HedrichInstitute for Molecular Plant Physiology and Biophysics, University of Würzburg, 97082, Würzburg, Germany. hedrich@botanik.uni-wuerzburg.de.
University of Würzburg · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEKing Saud University · SAUniversity of Freiburg · DEUniversity of Nottingham · GB

Funding

Biotechnology and Biological Sciences Research Council BB/G023972/1
6 · The paper itself

Abstract

Auxin is a key regulator of plant growth and development, but the causal relationship between hormone transport and root responses remains unresolved. Here we describe auxin uptake, together with early steps in signaling, in Arabidopsis root hairs. Using intracellular microelectrodes we show membrane depolarization, in response to IAA in a concentration- and pH-dependent manner. This depolarization is strongly impaired in aux1 mutants, indicating that AUX1 is the major transporter for auxin uptake in root hairs. Local intracellular auxin application triggers Ca

Indexed as

Gene Expression Regulation, PlantArabidopsisArabidopsis ProteinsBiological TransportCalciumCalcium SignalingCations, DivalentCyclic Nucleotide-Gated Cation ChannelsF-Box ProteinsHydrogen-Ion ConcentrationIndoleacetic AcidsMicroelectrodesMutationPlant Growth RegulatorsPlant RootsPlants, Genetically Modifiedalpha-(2,4-dimethylphenylethyl-2-oxo)indole-3-acetic acidArabidopsis ProteinsAUX1 protein, ArabidopsisCalciumCations, DivalentCNGC14 protein, ArabidopsisCyclic Nucleotide-Gated Cation ChannelsF-Box Proteinsindoleacetic acidIndoleacetic AcidsPlant Growth RegulatorsProtein IsoformsProto-Oncogene Proteins c-kitReceptors, Cell SurfaceTIR1 protein, Arabidopsis

Identifiers

PMID29563504
PMCPMC5862985
OpenAlexW2789294653

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.