Evidence map›Paper›PMID 29563183›Full record

ArticleGenes & development2018

Dendrite regeneration of adult

Laura DeVault, Tun Li, Sarah Izabel, Katherine L Thompson-Peer, Lily Yeh Jan, Yuh Nung Jan

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. The extracellular matrix genebioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Study of Axonal Injury and Degeneration inCold Spring Harbor protocols · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. A photo-switchable assay system for dendrite degeneration and repair inProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Laura DeVaultHoward Hughes Medical Institute, Department of Physiology, Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, California 94158, USA.ORCID 0000-0001-6801-5098
Tun LiHoward Hughes Medical Institute, Department of Physiology, Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, California 94158, USA.
Sarah IzabelHoward Hughes Medical Institute, Department of Physiology, Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, California 94158, USA.
Katherine L Thompson-PeerHoward Hughes Medical Institute, Department of Physiology, Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, California 94158, USA.ORCID 0000-0002-4200-3870
Lily Yeh JanHoward Hughes Medical Institute, Department of Physiology, Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, California 94158, USA.
Yuh Nung JanHoward Hughes Medical Institute, Department of Physiology, Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, California 94158, USA.
Howard Hughes Medical Institute · US

Funding

Dendrite morphogenesis, function and regenerationR35NS097227 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JAN, YUH NUNG · 2017 to 2024
$5.1M
Genetic Dissection of Dendrite DevelopmentR37NS040929 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JAN, YUH NUNG · 2010 to 2016
$2.5M
Mechanisms of Dendrite Regeneration after InjuryK99NS097627 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI THOMPSON-PEER, KATHERINE LOUISE · 2016 to 2017
$198k
Howard Hughes Medical InstituteNINDS NIH HHS K99 NS097627NINDS NIH HHS R35 NS097227NINDS NIH HHS R37 NS040929
6 · The paper itself

Abstract

Dendrites possess distinct structural and functional properties that enable neurons to receive information from the environment as well as other neurons. Despite their key role in neuronal function, current understanding of the ability of neurons to regenerate dendrites is lacking. This study characterizes the structural and functional capacity for dendrite regeneration in vivo in adult animals and examines the effect of neuronal maturation on dendrite regeneration. We focused on the class IV dendritic arborization (c4da) neuron of the

Indexed as

RegenerationAgingAnimalsDendritesDrosophilaDrosophila ProteinsEpidermisExtracellular MatrixGene Expression Regulation, DevelopmentalIntegrinsMatrix Metalloproteinase 2Sensory Receptor CellsDrosophila ProteinsIntegrinsMatrix Metalloproteinase 2adultagingdendriteregenerationremodelingtissue

Identifiers

PMID29563183
PMCPMC5900713
OpenAlexW2789232219

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.