Evidence map›Paper›PMID 29563177›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Relative Contributions of B Cells and Dendritic Cells from Lupus-Prone Mice to CD4

Seung-Chul Choi, Zhiwei Xu, Wei Li, Hong Yang, Derry C Roopenian, Herbert C Morse, Laurence Morel

Abstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Contribution of Dendritic Cell Subsets to T Cell-Dependent Responses in Mice.Journal of immunology (Baltimore, Md. : 1950) · 2022
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. IL-6: a cytokine at the crossroads of autoimmunity.Current opinion in immunology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Seung-Chul ChoiDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL 32610.ORCID 0000-0001-6230-9087
Zhiwei XuDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL 32610.
Wei LiDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL 32610.
Hong YangDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL 32610.
Derry C RoopenianThe Jackson Laboratory, Bar Harbor, ME 04609; and.
Herbert C MorseVirology and Cellular Immunology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852.ORCID 0000-0002-9331-3705
Laurence MorelDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL 32610; morel@ufl.edu.

Funding

Characterization of SLE-susceptibility loci on mouse chromosome 1R01AI045050 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Laurence Morel · 2000 to 2026
$11.5M
B Cell Development Defects in Murine LupusR01AI058150 · NIAID · UNIVERSITY OF FLORIDA · PI MOREL, LAURENCE · 2004 to 2014
$3.7M
Targeting follicular helper CD4 T cells in SLER01AI128901 · NIAID · UNIVERSITY OF FLORIDA · PI MOREL, LAURENCE · 2017 to 2021
$1.8M
NIAID NIH HHS R01 AI045050NIAID NIH HHS R01 AI058150NIAID NIH HHS R01 AI128901
6 · The paper itself

Abstract

Mouse models of lupus have shown that multiple immune cell types contribute to autoimmune disease. This study sought to investigate the involvement of B cells and dendritic cells in supporting the expansion of inflammatory and regulatory CD4

Indexed as

AnimalsB-LymphocytesCD4-Positive T-LymphocytesDendritic CellsDisease Models, AnimalLupus Erythematosus, SystemicLymphocyte ActivationMiceMice, Inbred C57BL

Identifiers

PMID29563177
PMCPMC5915918

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.