Evidence map›Paper›PMID 29563125›Full record

ArticleBMJ case reports2018

Sequential retinal necrosis secondary to varicella zoster in unrecognised long-standing HIV infection: patient safety report.

Brigid Ky Ning, Simon P Kelly, Celia Chu, Emile Morgan

Open access · hybridAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Brigid Ky NingDepartment of Ophthalmology, Royal Bolton Hospital NHS Foundation Trust, Bolton, UK.ORCID http://orcid.org/0000-0002-0608-6074
Simon P KellyDepartment of Ophthalmology, Royal Bolton Hospital NHS Foundation Trust, Bolton, UK.
Celia ChuDepartment of Microbiology, Royal Bolton Hospital NHS Foundation Trust, Bolton, UK.
Emile MorganDepartment of Genitourinary Medicine, Royal Bolton Hospital NHS Foundation Trust, Bolton, UK.
Bolton NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A retired woman with left ophthalmic shingles of over 2 years' duration attended with bilateral vision loss and systemic upset. Acute retinal necrosis with detachment was detected on right fundus examination. Cataract in left eye precluded funduscopy. Ocular ultrasonography revealed fibrotic retinal detachment in the left eye. MRI brain and orbits also showed signals of retinal detachment. No abnormal MRI signal within the optic nerve or brain was found. Varicella zoster virus was detected in ocular aqueous and blood samples. High-dose intravenous acyclovir was administered. HIV test was positive with a very low CD4 count. Antiretroviral medications were prescribed. There was no recovery of vision. She was certified as blind, and social services were involved in seeking to provide alterations to her home in view of her severe disability. This case highlights the importance of suspecting HIV in patients with severe or chronic ophthalmic shingles. Images and implications for clinical practice are presented.

Indexed as

AcyclovirAIDS-Related Opportunistic InfectionsAnti-Retroviral AgentsAntiviral AgentsBlindnessDiagnosis, DifferentialFemaleHerpes ZosterHIV InfectionsHumansMagnetic Resonance ImagingPatient SafetyRetinal DetachmentRetinal DiseasesRetinal Necrosis Syndrome, AcuteUltrasonographyAcyclovirAnti-Retroviral AgentsAntiviral AgentsHiv / Aidsophthalmologyretinasexual transmitted infections (viral)

Identifiers

PMID29563125
PMCPMC5878387
OpenAlexW2793449730

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.