Evidence map›Paper›PMID 29562898›Full record

ArticleBMC health services research2018

Embracing uncertainty, managing complexity: applying complexity thinking principles to transformation efforts in healthcare systems.

Sobia Khan, Ashley Vandermorris, John Shepherd, James W Begun, Holly Jordan Lanham, Mary Uhl-Bien, Whitney Berta

Abstract read
In one paragraph

Article in BMC health services research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Review
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  7. Article
  8. Systems leadership for quality in health care: from principles to actions.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2026
    Article
  9. Article
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  11. Complexity and Barriers to Vision Care: A Narrative Review Informed by a Mobile Eye Program.International journal of environmental research and public health · 2025
    Review
  12. Review
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  14. Multiagent AI Systems in Health Care: Envisioning Next-Generation Intelligence.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2025
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sobia KhanUniversity of Toronto, Toronto, ON, Canada. sob.khan@mail.utoronto.ca.
Ashley VandermorrisUniversity of Toronto, Toronto, ON, Canada.
John ShepherdUniversity of Toronto, Toronto, ON, Canada.
James W BegunDivision of Health Policy and Management, School of Public Health, University of Minnesota, Minneapolis, MN, USA.
Holly Jordan LanhamDepartment of Medicine, University of Texas Health Science Center, San Antonio, TX, USA.
Mary Uhl-BienNeeley School of Business, Texas Christian University, Forth Worth, TX, USA.
Whitney BertaUniversity of Toronto, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComplexity thinking is increasingly being embraced in healthcare, which is often described as a complex adaptive system (CAS). Applying CAS to healthcare as an explanatory model for understanding the nature of the system, and to stimulate changes and transformations within the system, is valuable. MAIN TEXT: A seminar series on systems and complexity thinking hosted at the University of Toronto in 2016 offered a number of insights on applications of CAS perspectives to healthcare that we explore here. We synthesized topics from this series into a set of six insights on how complexity thinking fosters a deeper understanding of accepted ideas in healthcare, applications of CAS to actors within the system, and paradoxes in applications of complexity thinking that may require further debate: 1) a complexity lens helps us better understand the nebulous term "context"; 2) concepts of CAS may be applied differently when actors are cognizant of the system in which they operate; 3) actor responses to uncertainty within a CAS is a mechanism for emergent and intentional adaptation; 4) acknowledging complexity supports patient-centred intersectional approaches to patient care; 5) complexity perspectives can support ways that leaders manage change (and transformation) in healthcare; and 6) complexity demands different ways of implementing ideas and assessing the system. To enhance our exploration of key insights, we augmented the knowledge gleaned from the series with key articles on complexity in the literature.

conclusionsUltimately, complexity thinking acknowledges the "messiness" that we seek to control in healthcare and encourages us to embrace it. This means seeing challenges as opportunities for adaptation, stimulating innovative solutions to ensure positive adaptation, leveraging the social system to enable ideas to emerge and spread across the system, and even more important, acknowledging that these adaptive actions are part of system behaviour just as much as periods of stability are. By embracing uncertainty and adapting innovatively, complexity thinking enables system actors to engage meaningfully and comfortably in healthcare system transformation.

Indexed as

Systems AnalysisDelivery of Health CareHumansUncertaintyComplex adaptive systemsComplexityHealth systemsSystems thinking

Identifiers

PMID29562898
PMCPMC5863365

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.