Evidence map›Paper›PMID 29562893›Full record

Trial reportBMC musculoskeletal disorders2018

No difference in the functional improvements between unilateral and bilateral total knee replacements.

Yu-Hao Huang, Chin Lin, Jia-Hwa Yang, Leou-Chyr Lin, Chih-Yuan Mou, Kwo-Tsao Chiang, Man-Gang Lee, Hsien-Feng Chang, Hsueh-Lu Chang, Wen Su and 4 more

Abstract readClinical TrialComparative Study
In one paragraph

Trial report in BMC musculoskeletal disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Recovery after Total Knee Arthroplasty: Does one or two knees matter?Journal of clinical orthopaedics and trauma · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yu-Hao HuangGraduate Institute of Medical Sciences, National Defense Medical Center, No.161, Min-Chun E. Rd., Sec. 6, Neihu, Taipei, 114, Taiwan, Republic of China.
Chin LinSchool of Public Health, National Defense Medical Center, No.161, Min-Chun E. Rd., Sec. 6, Neihu, Taipei, 114, Taiwan, Republic of China.
Jia-Hwa YangGraduate Institute of Life Sciences, National Defense Medical Center, No.161, Min-Chun E. Rd., Sec. 6, Neihu, Taipei, 114, Taiwan, Republic of China.
Leou-Chyr LinDepartment of Orthopedics, Tri-Service General Hospital and National Defense Medical Center, No.325, Sec.2, Chenggong Rd., Neihu District, Taipei, 114, Taiwan, Republic of China.
Chih-Yuan MouDepartment of Aviation Medicine and Physical examination, National Defense Medical Center and Tri-Service General Hospital Songshan Branch, No.131, Jiankang Rd., Songshan District, Taipei, 10581, Taiwan, Republic of China.
Kwo-Tsao ChiangSchool of Public Health, National Defense Medical Center, No.161, Min-Chun E. Rd., Sec. 6, Neihu, Taipei, 114, Taiwan, Republic of China.
Man-Gang LeeDepartment of Surgery, Zuoying Branch of Kaohsiung Armed Forces General Hospital, No.553, Junxiao Rd., Zuoying Dist., Kaohsiung City, 813, Taiwan, Republic of China.
Hsien-Feng ChangSchool of Public Health, National Defense Medical Center, No.161, Min-Chun E. Rd., Sec. 6, Neihu, Taipei, 114, Taiwan, Republic of China.
Hsueh-Lu ChangSchool of Public Health, National Defense Medical Center, No.161, Min-Chun E. Rd., Sec. 6, Neihu, Taipei, 114, Taiwan, Republic of China.
Wen SuDepartment of Nursing, Tri-Service General Hospital, No.161, Min-Chun E. Rd., Sec. 6, Neihu, Taipei, 114, Taiwan, Republic of China.
Shih-Jen YehDepartment of Research and Development, Da-Yeh University, No. 168, Xuefu Road, Dacun Township, Changhua County, 515, Taiwan, Republic of China.
Hung ChangDepartment of Physiology and Biophysics, National Defense Medical Center, No.325, Sec. 2, Chenggong Rd., Neihu District, Taipei City, 114, Taiwan, Republic of China.
Chih-Chien WangDepartment of Orthopedics, Tri-Service General Hospital and National Defense Medical Center, No.325, Sec.2, Chenggong Rd., Neihu District, Taipei, 114, Taiwan, Republic of China. tsghcc@yahoo.com.tw.
Sui-Lung SuSchool of Public Health, National Defense Medical Center, No.161, Min-Chun E. Rd., Sec. 6, Neihu, Taipei, 114, Taiwan, Republic of China. a131419@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDifferences between staged bilateral total knee replacement (TKR) and simultaneous bilateral TKR have been investigated, but few studies have investigated differences in the functional improvements resulting from these methods. Therefore, this study investigates the different functional improvements between staged bilateral total knee TKR and simultaneous bilateral TKR.

methodsAmong 144 potential bilateral TKR patients who were included in this study, 93 (64.6%) patients selected unilateral TKR and 51 (35.4%) selected bilateral TKR. Functional improvements were assessed using the Western Ontario and McMaster University osteoarthritis index (WOMAC) and the Medical Outcomes Trust Short Form-36 (SF-36), and patients were interviewed pre-operatively and after 6 months. A generalized equation was used to test for differences in functional improvements.

resultsAfter TKR, pain, stiffness, function and total WOMAC scores were significantly reduced in both groups, with mean changes from - 26.6 to - 41.4 and from - 27.5 to - 42.2.The mean health change of SF-36 scores, physical component and mental component scores changed to 45.2 ± 18.2, 74.0 ± 15.4 and 77.0 ± 9.6, respectively, in Group 1 and 47.1 ± 17.1, 74.0 ± 15.2 and 75.5 ± 12.1, respectively, in Group 2. Unilateral and simultaneous bilateral TKR produce similar functional improvements, although current work status may be a novel impact factor.

conclusionNo differences in functional improvements were identified between patients who selected unilateral versus bilateral TKR, indicating no recommendation for one procedure over the other.

Indexed as

AgedArthroplasty, Replacement, KneeFemaleHumansMaleMiddle AgedOsteoarthritis, KneeRecovery of FunctionTreatment OutcomeBilateral TKRFunctional improvementSF-36Total knee replacementUnilateral TKRWOMAC

Identifiers

PMID29562893
PMCPMC5861654

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.