Evidence map›Paper›PMID 29562725›Full record

ReviewInternational journal of molecular sciences2018

Genetic and Epigenetic Regulation in Nonalcoholic Fatty Liver Disease (NAFLD).

José A Del Campo, Rocío Gallego-Durán, Paloma Gallego, Lourdes Grande

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 2 pooled it
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 2 syntheses or guidelines pooled it, 146 citations in OpenAlex.

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  13. The Effects of Warm Acupuncture on the Expression ofCurrent issues in molecular biology · 2024
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27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

José A Del CampoValme University Hospital, Department of Digestive Diseases & CIBERehd, Servicio Andaluz de Salud, University of Sevilla, 41014 Sevilla, Spain. jantonio.delcampo@ciberehd.org.
Rocío Gallego-DuránInstituto de Biomedicina de Sevilla (IBiS) & CIBERehd, 41012 Sevilla, Spain. rociogallegoduran@gmail.com.
Paloma GallegoValme University Hospital, Department of Digestive Diseases & CIBERehd, Servicio Andaluz de Salud, University of Sevilla, 41014 Sevilla, Spain. palgalyer@alum.us.es.
Lourdes GrandeValme University Hospital, Department of Digestive Diseases & CIBERehd, Servicio Andaluz de Salud, University of Sevilla, 41014 Sevilla, Spain. lourdes.grande.sspa@juntadeandalucia.es.
Andalusian Health Service · ESInstituto de Biomedicina de Sevilla · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetics and epigenetics play a key role in the development of several diseases, including nonalcoholic fatty liver disease (NAFLD). Family studies demonstrate that first degree relatives of patients with NAFLD are at a much higher risk of the disease than the general population. The development of the Genome Wide Association Study (GWAS) technology has allowed the identification of numerous genetic polymorphisms involved in the evolution of diseases (e.g.,

Indexed as

Epigenesis, GeneticGenetic Predisposition to DiseaseDisease ProgressionDNA MethylationHumansNon-alcoholic Fatty Liver DiseasePolymorphism, Single NucleotideepigeneticsgeneticsmiRNAsNAFLDPNPLA3SIRT1

Identifiers

PMID29562725
PMCPMC5877772
OpenAlexW2792959572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.