Evidence map›Paper›PMID 29562597›Full record

Trial reportNutrients2018

Effects of Different Dietary Interventions on Calcitriol, Parathyroid Hormone, Calcium, and Phosphorus: Results from the DASH Trial.

Ahmed Hassoon, Erin D Michos, Edgar R Miller, Zeni Crisp, Lawrence J Appel

Abstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Review
  8. Article
  9. Environmental Factors That Affect Parathyroid Hormone and Calcitonin Levels.International journal of molecular sciences · 2021
    Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ahmed HassoonDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, , 615 N. Wolfe Street, Baltimore, MD 21205, USA. ahassoo1@jhu.edu.ORCID 0000-0002-4930-3331
Erin D MichosDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, , 615 N. Wolfe Street, Baltimore, MD 21205, USA. edonnell@jhmi.edu.
Edgar R MillerDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, , 615 N. Wolfe Street, Baltimore, MD 21205, USA. ermiller@jhmi.edu.
Zeni CrispPaul L. Foster School of Medicine, Texas Tech University Health Sciences Center, 5001 El Paso Drive, El Paso, TX 79905, USA. zeni.crisp@ttuhsc.edu.
Lawrence J AppelDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, , 615 N. Wolfe Street, Baltimore, MD 21205, USA. lappel@jhmi.edu.ORCID 0000-0002-0673-6823

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The "Dietary Approaches to Stop Hypertension" (DASH) diet, rich in fiber and low-fat dairy, effectively lowers blood pressure. DASH's effect on calcitriol and other markers of bone-mineral metabolism is unknown. This secondary analysis of the DASH trial aimed to determine the effect of dietary patterns on blood concentrations of calcitriol, parathyroid hormone (PTH), ionized calcium, and urinary excretion of calcium and phosphorus. Outcomes were available in 334 participants in the trial. After a 3-week run-in on the control diet, participants were randomized to control, fruits and vegetables (F&V), or DASH diets. Outcomes were assessed at the end of run-in, and during the last week of the intervention period. Mean age of participants was 45.7 ± 10.7 years, 46% female, and 57% African-American. Mean ± Standard Deviation(SD) baseline serum concentrations of calcitriol, PTH, and ionized calcium were 37.8 ± 9.2 pg/mL, 46.1 ± 18.5 pg/mL and 5.2 ± 0.23 mg/dL, respectively. Mean (±SD) urinary calcium and phosphorus excretions were 150.1 ± 77.8 and 708.0 ± 251.8 mg/24 h, respectively. Compared with control, DASH reduced calcitriol -3.32 pg/mL (

Indexed as

Dietary Approaches To Stop HypertensionDiet, HealthyFeeding BehaviorFruitVegetablesAdultCalcitriolCalciumFemaleHumansMaleMiddle AgedParathyroid HormonePhosphorusTime FactorsTreatment OutcomeCalcitriolCalciumParathyroid HormonePhosphorusPTH protein, humancalcitriolDASH trialparathyroid hormonevitamin D

Identifiers

PMID29562597
PMCPMC5872785

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.