Evidence map›Paper›PMID 29562238›Full record

ArticleNature2018

Moving magnetoencephalography towards real-world applications with a wearable system.

Elena Boto, Niall Holmes, James Leggett, Gillian Roberts, Vishal Shah, Sofie S Meyer, Leonardo Duque Muñoz, Karen J Mullinger, Tim M Tierney, Sven Bestmann and 3 more

Open access · greenAbstract read
In one paragraph

Article in Nature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 338 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
338citing papers in PubMed, 1 pooled it
72.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

338 citing papers in PubMed, 1 synthesis or guideline pooled it, 1,324 citations in OpenAlex.

  1. Pooled it
  2. From seeing to showing: towards a neuroscience of emotion production.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

278 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Elena BotoSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Niall HolmesSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
James LeggettSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Gillian RobertsSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Vishal ShahQuSpin Inc., 331 South 104th Street, Suite 130, Louisville, Colorado 80027, USA.
Sofie S MeyerWellcome Centre for Human Neuroimaging, UCL Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK.
Leonardo Duque MuñozWellcome Centre for Human Neuroimaging, UCL Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK.
Karen J MullingerSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Tim M TierneyWellcome Centre for Human Neuroimaging, UCL Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK.
Sven BestmannWellcome Centre for Human Neuroimaging, UCL Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK.
Gareth R BarnesWellcome Centre for Human Neuroimaging, UCL Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK.
Richard BowtellSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Matthew J BrookesSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
University of Nottingham · GBNational Hospital for Neurology and Neurosurgery · GBUniversity College London · GBQuSpin (United States) · USWellcome Centre for Human Neuroimaging · GB

Funding

High-resolution Non-cryogenic Magnetoencephalography: Systems-Level IntegrationR44MH110288 · NIMH · QUSPIN · PI SHAH, VISHAL K · 2016 to 2022
$5.1M
Adjustable Helmet Array for Neonatal MagnetoencephalographyR44HD074495 · NICHD · QUSPIN · PI SHAH, VISHAL K · 2014 to 2015
$1.5M
Medical Research Council MR/K005464/1Medical Research Council MR/M006301/1NICHD NIH HHS R44 HD074495NIMH NIH HHS R44 MH110288Wellcome Trust 203257BARNESWellcome Trust 203257/Z/16/Z
6 · The paper itself

Abstract

Imaging human brain function with techniques such as magnetoencephalography typically requires a subject to perform tasks while their head remains still within a restrictive scanner. This artificial environment makes the technique inaccessible to many people, and limits the experimental questions that can be addressed. For example, it has been difficult to apply neuroimaging to investigation of the neural substrates of cognitive development in babies and children, or to study processes in adults that require unconstrained head movement (such as spatial navigation). Here we describe a magnetoencephalography system that can be worn like a helmet, allowing free and natural movement during scanning. This is possible owing to the integration of quantum sensors, which do not rely on superconducting technology, with a system for nulling background magnetic fields. We demonstrate human electrophysiological measurement at millisecond resolution while subjects make natural movements, including head nodding, stretching, drinking and playing a ball game. Our results compare well to those of the current state-of-the-art, even when subjects make large head movements. The system opens up new possibilities for scanning any subject or patient group, with myriad applications such as characterization of the neurodevelopmental connectome, imaging subjects moving naturally in a virtual environment and investigating the pathophysiology of movement disorders.

Indexed as

MovementWearable Electronic DevicesAdultDrinkingFemaleHeadHumansMagnetic FieldsMagnetoencephalographySports

Identifiers

PMID29562238
PMCPMC6063354
OpenAlexW2791548393

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.