Evidence map›Paper›PMID 29562230›Full record

ArticleNature2018

Encoding of danger by parabrachial CGRP neurons.

Carlos A Campos, Anna J Bowen, Carolyn W Roman, Richard D Palmiter

Abstract read
In one paragraph

Article in Nature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 182 papers.

0numbers the graph read from it
0cells of the map it votes in
182citing papers in PubMed
40.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

182 citing papers in PubMed, 329 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. ParabrachialProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Supraspinal Circuit Mechanisms Underlying Itch Processing.CNS neuroscience & therapeutics · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Parabrachial CGRP Neurons Regulate Opioid Reinforcement.bioRxiv : the preprint server for biology · 2026
    Article
  12. Article
  13. Article
  14. Brain-immune interactions generate pathogen-specific sickness states.bioRxiv : the preprint server for biology · 2025
    Article
  15. Article
  16. Article
  17. Multimodal Breathing Control: Pontomedullary Mechanisms and Current Perspectives.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  18. Ingestion-activated CGRP neurons control learning but not satiety.bioRxiv : the preprint server for biology · 2025
    Article
  19. ParabrachialeNeuro · 2025
    Article
  20. Review

122 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Carlos A CamposHoward Hughes Medical Institute and Department of Biochemistry, University of Washington, Seattle, Washington 98195, USA.
Anna J BowenHoward Hughes Medical Institute and Department of Biochemistry, University of Washington, Seattle, Washington 98195, USA.
Carolyn W RomanHoward Hughes Medical Institute and Department of Biochemistry, University of Washington, Seattle, Washington 98195, USA.
Richard D PalmiterHoward Hughes Medical Institute and Department of Biochemistry, University of Washington, Seattle, Washington 98195, USA.
Howard Hughes Medical Institute · USUniversity of Washington · US

Funding

Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Karin E Bornfeldt · 1986 to 2026
$41.4M
Diabetes, Obesity and Metabolism Training ProgramT32DK007247 · NIDDK · UNIVERSITY OF WASHINGTON · PI GREGORY J MORTON, KRISTINA Marie UTZSCHNEIDER · 1986 to 2026
$10.0M
Effect of Killing or Removing GABA from NPY/AgRP NeuronsR01DA024908 · NIDA · UNIVERSITY OF WASHINGTON · PI PALMITER, RICHARD D. · 2007 to 2021
$3.5M
NIDA NIH HHS R01 DA024908NIDDK NIH HHS P30 DK017047NIDDK NIH HHS T32 DK007247
6 · The paper itself

Abstract

Animals must respond to various threats to survive. Neurons that express calcitonin gene-related peptide in the parabrachial nucleus (CGRP

Indexed as

AnimalsAvoidance LearningCalcitonin Gene-Related PeptideCalcium SignalingConditioning, ClassicalDiet, High-FatElectroshockFearHeat-Shock ResponseLipopolysaccharidesMaleMental RecallMiceNeuronsPainParabrachial NucleusCalcitonin Gene-Related PeptideLipopolysaccharides

Identifiers

PMID29562230
PMCPMC6129987
OpenAlexW2793823359

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.