Evidence map›Paper›PMID 29561881›Full record

ArticlePloS one2018

Artificial selection increased body weight but induced increase of runs of homozygosity in Hanwoo cattle.

Kwondo Kim, Jaehoon Jung, Kelsey Caetano-Anollés, Samsun Sung, DongAhn Yoo, Bong-Hwan Choi, Hyung-Chul Kim, Jin-Young Jeong, Yong-Min Cho, Eung-Woo Park and 4 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Genotypic and phenotypic consequences of domestication in dogs.bioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Kwondo KimInterdisciplinary Program in Bioinformatics, Seoul National University, Kwan-ak Gu, Seoul, Republic of Korea.
Jaehoon JungC&K genomics, C-1008, H businesspark, 26, Beobwon-ro 9-gil, Songpa-gu, Seoul, Republic of Korea.
Kelsey Caetano-AnollésDepartment of Agricultural Biotechnology, Animal Biotechnology Major, and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Korea.
Samsun SungC&K genomics, C-1008, H businesspark, 26, Beobwon-ro 9-gil, Songpa-gu, Seoul, Republic of Korea.
DongAhn YooInterdisciplinary Program in Bioinformatics, Seoul National University, Kwan-ak Gu, Seoul, Republic of Korea.
Bong-Hwan ChoiNational Institute of Animal Science, Rural Development Administration, Wanju, Republic of Korea.
Hyung-Chul KimNational Institute of Animal Science, Rural Development Administration, Wanju, Republic of Korea.
Jin-Young JeongNational Institute of Animal Science, Rural Development Administration, Wanju, Republic of Korea.
Yong-Min ChoNational Institute of Animal Science, Rural Development Administration, Wanju, Republic of Korea.
Eung-Woo ParkNational Institute of Animal Science, Rural Development Administration, Wanju, Republic of Korea.
Tae-Jeong ChoiNational Institute of Animal Science, Rural Development Administration, Wanju, Republic of Korea.
Byoungho ParkNational Institute of Animal Science, Rural Development Administration, Wanju, Republic of Korea.
Dajeong LimNational Institute of Animal Science, Rural Development Administration, Wanju, Republic of Korea.
Heebal KimInterdisciplinary Program in Bioinformatics, Seoul National University, Kwan-ak Gu, Seoul, Republic of Korea.ORCID 0000-0003-3064-1303
Seoul National University · KRRural Development Administration · KRCrystalGenomics (South Korea) · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial selection has been demonstrated to have a rapid and significant effect on the phenotype and genome of an organism. However, most previous studies on artificial selection have focused solely on genomic sequences modified by artificial selection or genomic sequences associated with a specific trait. In this study, we generated whole genome sequencing data of 126 cattle under artificial selection, and 24,973,862 single nucleotide variants to investigate the relationship among artificial selection, genomic sequences and trait. Using runs of homozygosity detected by the variants, we showed increase of inbreeding for decades, and at the same time demonstrated a little influence of recent inbreeding on body weight. Also, we could identify ~0.2 Mb runs of homozygosity segment which may be created by recent artificial selection. This approach may aid in development of genetic markers directly influenced by artificial selection, and provide insight into the process of artificial selection.

Indexed as

HomozygoteInbreedingSelection, GeneticAnimalsBody WeightCattleGenomeGenomicsGenotypeMalePhenotypePolymorphism, Single Nucleotide

Identifiers

PMID29561881
PMCPMC5862439
OpenAlexW2790454230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.