Evidence map›Paper›PMID 29561803›Full record

ArticleMolecules (Basel, Switzerland)2018

Synthesis of Some Novel Thiadiazole Derivative Compounds and Screening Their Antidepressant-Like Activities.

Nafiz Öncü Can, Özgür Devrim Can, Derya Osmaniye, Ümide Demir Özkay

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nafiz Öncü CanDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. nafizoc@anadolu.edu.tr.ORCID 0000-0003-0280-518X
Özgür Devrim CanDepartment of Pharmacology, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. ozgurdt@anadolu.edu.tr.
Derya OsmaniyeDoping and Narcotic Compounds Analysis Laboratory, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. dosmaniye@anadolu.edu.tr.
Ümide Demir ÖzkayDepartment of Pharmacology, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. udemir@anadolu.edu.tr.
Anadolu University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel thiadiazole derivatives were synthesized through the reaction of acetylated 2-aminothiadiazole and piperazine derivatives. The chemical structures of the compounds were clarified by Infrared Spectroscopy (IR), ¹H Nuclear Magnetic Resonance Spectroscopy (¹H-NMR),

Indexed as

Drug Evaluation, PreclinicalAnimalsAntidepressive AgentsFluoxetineHindlimb SuspensionMaleMice, Inbred BALB CMotor ActivitySwimmingThiadiazolesAntidepressive AgentsFluoxetineThiadiazolesactivity cagemodified forced swimmingtail-suspensionthiadiazole

Identifiers

PMID29561803
PMCPMC6017710
OpenAlexW2789639466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.