Evidence map›Paper›PMID 29561785›Full record

ArticleToxins2018

Cyanobacteria Scytonema javanicum and Scytonema ocellatum Lipopolysaccharides Elicit Release of Superoxide Anion, Matrix-Metalloproteinase-9, Cytokines and Chemokines by Rat Microglia In Vitro.

Lucas C Klemm, Evan Czerwonka, Mary L Hall, Philip G Williams, Alejandro M S Mayer

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lucas C KlemmBiomedical Sciences Program, College of Health Sciences, Midwestern University, Downers Grove, IL 60515, USA. lklemm@wisc.edu.
Evan CzerwonkaDepartment of Pharmacology, Chicago College of Osteopathic Medicine, Midwestern University, Downers Grove, IL 60515, USA. eczerwonka79@midwestern.edu.
Mary L HallDepartment of Pharmacology, Chicago College of Osteopathic Medicine, Midwestern University, Downers Grove, IL 60515, USA. mhallx@midwestern.edu.
Philip G WilliamsDepartment of Chemistry, University of Hawaii at Manoa, Honolulu, HI 96882, USA. philipwi@hawaii.edu.
Alejandro M S MayerDepartment of Pharmacology, Chicago College of Osteopathic Medicine, Midwestern University, Downers Grove, IL 60515, USA. amayer@midwestern.edu.
Midwestern University · USUniversity of Hawaiʻi at Mānoa · US

Funding

Capture the Inhibitor: Affinity Approaches to the Discovery of Secretase LeadsR01AG039468 · NIA · UNIVERSITY OF HAWAII AT MANOA · PI WILLIAMS, PHILIP · 2011 to 2014
$1.1M
NIA NIH HHS R01 AG039468
6 · The paper itself

Abstract

Cosmopolitan Gram-negative cyanobacteria may affect human and animal health by contaminating terrestrial, marine and freshwater environments with toxins, such as lipopolysaccharide (LPS). The cyanobacterial genus

Indexed as

CyanobacteriaAnimalsAnimals, NewbornCytokinesLipopolysaccharidesMatrix Metalloproteinase 9MicrogliaRats, Sprague-DawleySuperoxidesCytokinesLipopolysaccharidesMatrix Metalloproteinase 9Mmp9 protein, ratSuperoxideschemokinecyanobacteriumcytokinelipopolysaccharidemicrogliaMMP-9ratScytonemasuperoxide

Identifiers

PMID29561785
PMCPMC5923296
OpenAlexW2783050039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.