Evidence map›Paper›PMID 29561662›Full record

ArticleAmerican journal of physiology. Cell physiology2018

Dextran sulfate sodium-induced chronic colitis attenuates Ca

Trey S Rottgen, Andrew J Nickerson, Emily A Minor, Amanda B Stewart, Abby D Harold, Vazhaikkurichi M Rajendran

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. CaActa physiologica (Oxford, England) · 2026
    Review
  2. Review
  3. Article
  4. Dietary NaCellular and molecular life sciences : CMLS · 2023
    Article
  5. Article
  6. The CaActa pharmaceutica Sinica. B · 2021
    Review
  7. Activation ofAmerican journal of physiology. Cell physiology · 2021
    Article
  8. Goblet cell LRRC26 regulates BK channel activation and protects against colitis in mice.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  9. Dual role of CaCell death & disease · 2020
    Article
  10. Article
  11. Article
  12. Calcium-Activated ClInternational journal of molecular sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Trey S RottgenDepartment of Physiology, Pharmacology, and Neuroscience, West Virginia University School of Medicine , Morgantown, West Virginia.
Andrew J NickersonDepartment of Physiology, Pharmacology, and Neuroscience, West Virginia University School of Medicine , Morgantown, West Virginia.
Emily A MinorDepartment of Physiology, Pharmacology, and Neuroscience, West Virginia University School of Medicine , Morgantown, West Virginia.
Amanda B StewartDepartment of Biology, Bethany College, Bethany, West Virginia.
Abby D HaroldDepartment of Physiology, Pharmacology, and Neuroscience, West Virginia University School of Medicine , Morgantown, West Virginia.
Vazhaikkurichi M RajendranDepartment of Physiology, Pharmacology, and Neuroscience, West Virginia University School of Medicine , Morgantown, West Virginia.
West Virginia University · USBethany College - West Virginia · US

Funding

Role of IK channels in rat distal colonR01DK018777 · NIDDK · YALE UNIVERSITY · PI RAJENDRAN, VAZHAIKKURICHI M. · 1986 to 2010
$2.5M
Role of BK Channels in K+-driven Colonic Water Secretion in Health and DiseaseR01DK104791 · NIDDK · WEST VIRGINIA UNIVERSITY · PI RAJENDRAN, VAZHAIKKURICHI M. · 2015 to 2019
$1.7M
NIDDK NIH HHS R01 DK018777NIDDK NIH HHS R01 DK104791
6 · The paper itself

Abstract

Attenuated Ca

Indexed as

AnimalsAnoctamin-1BestrophinsCalciumCarbacholChloride ChannelsChloridesColitisColonCystic FibrosisDextran SulfateDown-RegulationIntestinal MucosaMaleMiceMice, Inbred BALB CANO1 protein, mouseAnoctamin-1BestrophinsCalciumCarbacholChloride ChannelsChloridesDextran SulfateReceptor, Muscarinic M3channelsCl−colitiscolonic epithelium, muscarinic signalingUssing chamber

Identifiers

PMID29561662
PMCPMC6087728
OpenAlexW2792843843

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.