Evidence map›Paper›PMID 29561497›Full record

Trial reportOptometry and vision science : official publication of the American Academy of Optometry2018

Visual Acuity and Over-refraction in Myopic Children Fitted with Soft Multifocal Contact Lenses.

Krystal L Schulle, David A Berntsen, Loraine T Sinnott, Katherine M Bickle, Anita T Gostovic, Gilbert E Pierce, Lisa A Jones-Jordan, Donald O Mutti, Jeffrey J Walline, Bifocal Lenses in Nearsighted Kids (BLINK) Study Group

Abstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Optometry and vision science : official publication of the American Academy of Optometry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Interventions to slow progression of myopia in children.The Cochrane database of systematic reviews · 2020
    Pooled it
  2. Bifocal & Atropine in Myopia Study: Baseline Data and Methods.Optometry and vision science : official publication of the American Academy of Optometry · 2019
    Trial
  3. Trial
  4. Accuracy and precision of a sphero-cylindrical over-refraction app for smartphones.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Article
  5. The effect of pupil size on visual performance with center-distance soft multifocal contact lenses.Optometry and vision science : official publication of the American Academy of Optometry · 2025
    Article
  6. Article
  7. Peripheral Defocus and Myopia Management: A Mini-Review.Korean journal of ophthalmology : KJO · 2023
    Review
  8. IMI Prevention of Myopia and Its Progression.Investigative ophthalmology & visual science · 2021
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Krystal L SchulleUniversity of Houston College of Optometry, Houston, Texas.
David A Berntsen
Loraine T SinnottThe Ohio State University College of Optometry, Columbus, Ohio *dberntsen@uh.edu.
Katherine M BickleThe Ohio State University College of Optometry, Columbus, Ohio *dberntsen@uh.edu.
Anita T GostovicUniversity of Houston College of Optometry, Houston, Texas.
Gilbert E PierceThe Ohio State University College of Optometry, Columbus, Ohio *dberntsen@uh.edu.
Lisa A Jones-JordanThe Ohio State University College of Optometry, Columbus, Ohio *dberntsen@uh.edu.
Donald O MuttiThe Ohio State University College of Optometry, Columbus, Ohio *dberntsen@uh.edu.
Jeffrey J WallineThe Ohio State University College of Optometry, Columbus, Ohio *dberntsen@uh.edu.
Bifocal Lenses in Nearsighted Kids (BLINK) Study Group
University of Houston · USThe Ohio State University · USTokyo Medical Examiner's Office · JPThe Coordinating Center · US

Funding

The Ohio State University Center for clinical and Translational ScienceUL1TR001070 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2013 to 2017
$22.6M
Research Programming ModuleP30EY007551 · NEI · UNIVERSITY OF HOUSTON · PI LAURA J. FRISHMAN · 1988 to 2026
$16.4M
Soft Bifocal Contact Lens Myopia Control - Clincal CenterU10EY023210 · NEI · OHIO STATE UNIVERSITY · PI MUTTI, DONALD O. · 2014 to 2018
$2.9M
Soft Bifocal Contact Lens Myopia ControlU10EY023204 · NEI · UNIVERSITY OF HOUSTON · PI BERNTSEN, DAVID A · 2014 to 2018
$2.6M
Examination of Myopia Progression and Consequences and Mechanism of Soft Multifocal Contact Lens Myopia Control - Clinical CenterUG1EY023210 · NEI · OHIO STATE UNIVERSITY · PI MUTTI, DONALD O. · 2019 to 2023
$2.6M
Soft Bifocal Contact Lens Myopia Control - Data Coordinating CenterU10EY023206 · NEI · OHIO STATE UNIVERSITY · PI JORDAN, LISA A · 2014 to 2018
$1.8M
Soft Bifocal Contact Lens Myopia Control - Study ChairU10EY023208 · NEI · OHIO STATE UNIVERSITY · PI WALLINE, JEFFREY JAY · 2014 to 2018
$742k
Examination of Myopia Progression and Consequences and Mechanism of Soft Multifocal Contact Lens Myopia ControlUG1EY023208 · NEI · OHIO STATE UNIVERSITY · PI WALLINE, JEFFREY JAY · 2019 to 2023
$678k
NCATS NIH HHS UL1 TR001070NEI NIH HHS P30 EY007551NEI NIH HHS U10 EY023204NEI NIH HHS U10 EY023206NEI NIH HHS U10 EY023208NEI NIH HHS U10 EY023210NEI NIH HHS UG1 EY023208NEI NIH HHS UG1 EY023210
6 · The paper itself

Abstract

significancePractitioners fitting contact lenses for myopia control frequently question whether a myopic child can achieve good vision with a high-add multifocal. We demonstrate that visual acuity is not different than spectacles with a commercially available, center-distance soft multifocal contact lens (MFCL) (Biofinity Multifocal "D"; +2.50 D add). PURPOSE: To determine the spherical over-refraction (SOR) necessary to obtain best-corrected visual acuity (BCVA) when fitting myopic children with a center-distance soft MFCL.

methodsChildren (n = 294) aged 7 to 11 years with myopia (spherical component) of -0.75 to -5.00 diopters (D) (inclusive) and 1.00 D cylinder or less (corneal plane) were fitted bilaterally with +2.50 D add Biofinity "D" MFCLs. The initial MFCL power was the spherical equivalent of a standardized subjective refraction, rounded to the nearest 0.25 D step (corneal plane). An SOR was performed monocularly (each eye) to achieve BCVA. Binocular, high-contrast logMAR acuity was measured with manifest spectacle correction and MFCLs with over-refraction. Photopic pupil size was measured with a pupilometer.

resultsThe mean (±SD) age was 10.3 ± 1.2 years, and the mean (±SD) SOR needed to achieve BCVA was OD: -0.61 ± 0.24 D/OS: -0.58 ± 0.27 D. There was no difference in binocular high-contrast visual acuity (logMAR) between spectacles (-0.01 ± 0.06) and best-corrected MFCLs (-0.01 ± 0.07) (P = .59). The mean (±SD) photopic pupil size (5.4 ± 0.7 mm) was not correlated with best MFCL correction or the over-refraction magnitude (both P ≥ .09).

conclusionsChildren achieved BCVA with +2.50 D add MFCLs that was not different than with spectacles. Children typically required an over-refraction of -0.50 to -0.75 D to achieve BCVA. With a careful over-refraction, these +2.50 D add MFCLs provide good distance acuity, making them viable candidates for myopia control.

Indexed as

Contact Lenses, HydrophilicChildDouble-Blind MethodEyeglassesFemaleHumansMaleMyopiaProsthesis FittingPupilRefraction, OcularVision TestsVisual Acuity

Identifiers

PMID29561497
PMCPMC5880703
OpenAlexW2792922215

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.