ArticleOrganic letters2018
Enantioselective Synthesis of Pyrrolopyrimidine Scaffolds through Cation-Directed Nucleophilic Aromatic Substitution.
Article in Organic letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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Who cites it
13 citing papers in PubMed.
- Directed evolution of an enantiocomplementary SNature communications · 2026Article
- Recent Advances in Organocatalytic Kinetic Resolution for the Synthesis of Axially Chiral Compounds.Molecules (Basel, Switzerland) · 2026Review
- Nucleophilic aromatic substitutions enable diversity-oriented synthesis of heterocyclic atropisomers via non-atropisomeric intermediates.Nature communications · 2025Article
- Phase-transfer-catalyst enabled enantioselective C-N coupling to access chiral boron-stereogenic BODIPYs.Nature communications · 2025Article
- Article
- Bifunctional Squaramide-Catalyzed Oxidative Kinetic Resolution: Simultaneous Access to Axially Chiral Thioether and Sulfoxide.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Catalytic Enantioselective Synthesis of Axially Chiral Imidazoles by Cation-Directed Desymmetrization.Journal of the American Chemical Society · 2023Article
- Targeting the RET tyrosine kinase in neuroblastoma: A review and application of a novel selective drug design strategy.Biochemical pharmacology · 2023Review
- Dynamic Kinetic Resolution of Indole-Based Sulfenylated Heterobiaryls by Rhodium-Catalyzed Atroposelective Reductive Aldol Reaction.ACS catalysis · 2023Article
- Atropisomerism in the Pharmaceutically Relevant Realm.Accounts of chemical research · 2022Article
- Catalytic atroposelective dynamic kinetic resolutions and kinetic resolutions towards 3-arylquinolinesChemical communications (Cambridge, England) · 2021Article
- Towards a Catalytic Atroposelective Synthesis of Diaryl Ethers via C(Synlett : accounts and rapid communications in synthetic organic chemistry · 2018Article
- Enantioselective Synthesis of Biaryl Atropisomers via the Addition of Thiophenols into Aryl-Naphthoquinones.ACS catalysis · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The catalytic enantioselective synthesis of 3-aryl-substituted pyrrolopyrimidines (PPYs), a common motif in drug discovery, is achieved through a kinetic resolution via quaternary ammonium salt-catalyzed nucleophilic aromatic substitution (S
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.