Evidence map›Paper›PMID 29560914›Full record

ArticleBiological psychiatry. Cognitive neuroscience and neuroimaging2017

Using Polygenic Risk Scores to Establish Endophenotypes: Considerations and Current Constraints.

David C Glahn, Andrew M McIntosh

Abstract readComment
In one paragraph

Article in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Violence exposure in an urban city: A GxE interaction with aggressive and impulsive behaviors.Journal of child psychology and psychiatry, and allied disciplines · 2019
    Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

David C GlahnDepartment of Psychiatry, Yale University School of Medicine, New Haven; Olin Neuropsychiatry Research Center, Institute of Living, Hartford, Connecticut. Electronic address: david.glahn@yale.edu.
Andrew M McIntoshDivision of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, United Kingdom.

Funding

Large-Scale Evaluation of the Effect of Rare Genetic Variants on Psychiatric Symptoms and Cognitive AbilityU01MH119690 · NIMH · BOSTON CHILDREN'S HOSPITAL · PI ALMASY, LAURA A., GLAHN, DAVID C · 2019 to 2023
$5.9M
Genetics of Brain Structure and FunctionR01MH078143 · NIMH · YALE UNIVERSITY · PI GLAHN, DAVID C · 2006 to 2014
$4.3M
Gene Networks Influencing Psychotic Dysconnectivity in African AmericansR01MH106324 · NIMH · YALE UNIVERSITY · PI BLANGERO, JOHN, GLAHN, DAVID C · 2015 to 2019
$4.2M
Genetics of Brain Structure and Function: Genome-Wide AssociationR01MH083824 · NIMH · YALE UNIVERSITY · PI GLAHN, DAVID C · 2008 to 2013
$3.3M
Influence of Psychosis on Brain-Behavior Endophenotypes for Bipolar DisorderR01MH080912 · NIMH · YALE UNIVERSITY · PI GLAHN, DAVID C · 2008 to 2012
$2.6M
1/3:Pedigree-Based Whole Genome Sequencing of Affective and Psychotic DisordersU01MH105630 · NIMH · YALE UNIVERSITY · PI GLAHN, DAVID C · 2015 to 2018
$1.4M
Chief Scientist Office SCD/12National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/C011202/1NIMH NIH HHS R01 MH078143NIMH NIH HHS R01 MH080912NIMH NIH HHS R01 MH083824NIMH NIH HHS R01 MH106324NIMH NIH HHS U01 MH105630NIMH NIH HHS U01 MH119690
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID29560914
PMCPMC7731074

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.