Evidence map›Paper›PMID 29560783›Full record

ArticleChannels (Austin, Tex.)2018

TRPC6 and TRPC4 Heteromultimerization Mediates Store Depletion-Activated NCX1 Reversal in Proliferative Vascular Smooth Muscle Cells.

Bin Zhang, Bei Liu, Carolyn M Roos, Michael A Thompson, Y S Prakash, Jordan D Miller, Rui-Wei Guo

Open access · goldAbstract read
In one paragraph

Article in Channels (Austin, Tex.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
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  4. NaEuropean journal of pharmacology · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Bin Zhanga Division of Cardiovascular Surgery, Mayo Clinic, Rochester, MN, USA; and Department of Physiology , Mayo Clinic , Rochester , MN , USA.
Bei Liub Department of Obstetrics and Gynecology , Kunming General Hospital of Chengdu Military Command , Kunming , Yunnan , China.
Carolyn M Roosa Division of Cardiovascular Surgery, Mayo Clinic, Rochester, MN, USA; and Department of Physiology , Mayo Clinic , Rochester , MN , USA.
Michael A Thompsonc Department of Anesthesiology , Mayo Clinic , Rochester , Minnesota , USA.
Y S Prakashc Department of Anesthesiology , Mayo Clinic , Rochester , Minnesota , USA.
Jordan D Millera Division of Cardiovascular Surgery, Mayo Clinic, Rochester, MN, USA; and Department of Physiology , Mayo Clinic , Rochester , MN , USA.
Rui-Wei Guod Department of Cardiology , Kunming General Hospital of Chengdu Military Command , Kunming , Yunnan , China.
Mayo Clinic · USKunming General Hospital of Chengdu Military Command · CNMayo Clinic in Arizona · US

Funding

Aging and Resiliency in Mice: Optimizing Assessment Protocols and Testing InterventionsR01AG053832 · NIA · MAYO CLINIC ROCHESTER · PI LEBRASSEUR, NATHAN K, MILLER, JORDAN D · 2016 to 2020
$2.0M
Role of SIRT6 in calcific aortic valve diseaseR01HL111121 · NHLBI · MAYO CLINIC ROCHESTER · PI MILLER, JORDAN D · 2013 to 2017
$2.0M
NHLBI NIH HHS R01 HL111121NIA NIH HHS R01 AG053832
6 · The paper itself

Abstract

Store depletion has been shown to induce Ca

Indexed as

AnimalsCell ProliferationCells, CulturedMyocytes, Smooth MuscleRatsSodium-Calcium ExchangerTRPC Cation ChannelsSodium-Calcium Exchangersodium-calcium exchanger 1TRPC4 ion channelTrpc6 protein, ratTRPC Cation ChannelsNa+/Ca2+ exchangestore-operated calcium channelstransient receptor potential canonicalvascular smooth muscle cells

Identifiers

PMID29560783
PMCPMC5972809
OpenAlexW2793623121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.