Evidence map›Paper›PMID 29560214›Full record

ArticleChemical science2015

Ternary DNA computing using 3 × 3 multiplication matrices.

Ron Orbach, Sivan Lilienthal, Michael Klein, R D Levine, Francoise Remacle, Itamar Willner

Abstract read
In one paragraph

Article in Chemical science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  7. Continuous variables logicChemical science · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ron OrbachInstitute of Chemistry , The Hebrew University of Jerusalem , Jerusalem 91904 , Israel . Email: willnea@vms.huji.ac.il.
Sivan LilienthalInstitute of Chemistry , The Hebrew University of Jerusalem , Jerusalem 91904 , Israel . Email: willnea@vms.huji.ac.il.
Michael KleinInstitute of Chemistry , The Hebrew University of Jerusalem , Jerusalem 91904 , Israel . Email: willnea@vms.huji.ac.il.
R D LevineInstitute of Chemistry , The Hebrew University of Jerusalem , Jerusalem 91904 , Israel . Email: willnea@vms.huji.ac.il.
Francoise RemacleChemistry Department , University of Liège , B6c , 4000 Liège , Belgium.
Itamar WillnerInstitute of Chemistry , The Hebrew University of Jerusalem , Jerusalem 91904 , Israel . Email: willnea@vms.huji.ac.il.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-Boolean computations implementing operations on multi-valued variables beyond base 2 allow enhanced computational complexity. We introduce DNA as a functional material for ternary computing, and in particular demonstrate the use of three-valued oligonucleotide inputs to construct a 3 × 3 multiplication table. The system consists of two three-valued inputs of -1; 0; +1 and a fluorophore/quencher functional hairpin acting as computational and reporter module. The interaction of the computational hairpin module with the different values of the inputs yields a 3 × 3 multiplication matrix consisting of nine nanostructures that are read out by three distinct fluorescence intensities. By combining three different hairpin computational modules, each modified with a different fluorophore/quencher pair, and using different sets of inputs, the parallel operation of three multiplication tables is demonstrated.

Identifiers

PMID29560214
PMCPMC5811156

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.