ArticleChemical science2015
Flow chemistry as a discovery tool to access sp
Article in Chemical science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Redox Approaches to Carbene Generation in Catalytic Cyclopropanation Reactions.Angewandte Chemie (International ed. in English) · 2024Review
- Mechanism of Asymmetric Homologation of Alkenylboronic Acids with CFThe Journal of organic chemistry · 2024Article
- Continuous flow synthesis enabling reaction discovery.Chemical science · 2024Review
- Synthesis of substituted benzylboronates by light promoted homologation of boronic acids withChemical science · 2023Article
- Hydrolysis-Resistant Ester-Based Linkers for Development of Activity-Based NIR Bioluminescence Probes.Journal of the American Chemical Society · 2023Article
- In-situ Kinetic Studies of Rh(II)-Catalyzed C-H Functionalization to Achieve High Catalyst Turnover Numbers.ACS catalysis · 2022Article
- Unlocking a Diazirine Long-Lived Nuclear Singlet State via Photochemistry: NMR Detection and Lifetime of an Unstabilized Diazo-Compound.Journal of the American Chemical Society · 2018Article
- Expanding the medicinal chemistry synthetic toolbox.Nature reviews. Drug discovery · 2018Review
- A Versatile Route to Unstable Diazo Compounds via Oxadiazolines and their Use in Aryl-Alkyl Cross-Coupling Reactions.Angewandte Chemie (International ed. in English) · 2017Article
- Unveiling the role of boroxines in metal-free carbon-carbon homologations using diazo compounds and boronic acids.Chemical science · 2017Article
- Rapid Asymmetric Synthesis of Disubstituted Allenes by Coupling of Flow-Generated Diazo Compounds and Propargylated Amines.Angewandte Chemie (International ed. in English) · 2017Article
- Contribution of microreactor technology and flow chemistry to the development of green and sustainable synthesis.Beilstein journal of organic chemistry · 2017Review
- A multicomponent approach for the preparation of homoallylic alcohols.Chemical science · 2016Article
- Visible Light Activation of Boronic Esters Enables Efficient Photoredox C(spAngewandte Chemie (International ed. in English) · 2016Article
- Exploring Flow Procedures for Diazonium Formation.Molecules (Basel, Switzerland) · 2016Article
- Iterative reactions of transient boronic acids enable sequential C-C bond formation.Nature chemistry · 2016Article
- Enabling Technologies for the Future of Chemical Synthesis.ACS central science · 2016Review
- Micro-total envelope system with silicon nanowire separator for safe carcinogenic chemistry.Nature communications · 2016Article
- Continuous-flow synthesis of primary amines: Metal-free reduction of aliphatic and aromatic nitro derivatives with trichlorosilane.Beilstein journal of organic chemistry · 2016Article
- Practical and economic lithiations of functionalized arenes and heteroarenes using CyChemical science · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The work takes advantage of an important feature of flow chemistry, whereby the generation of a transient species (or reactive intermediate) can be followed by a transfer step into another chemical environment, before the intermediate is reacted with a coupling partner. This concept is successfully applied to achieve a room temperature sp
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.