Evidence map›Paper›PMID 29560098›Full record

ArticleOncotarget2018

Fucoidan-coated CuS nanoparticles for chemo-and photothermal therapy against cancer.

Bian Jang, Madhappan Santha Moorthy, Panchanathan Manivasagan, Li Xu, Kyeongeun Song, Kang Dae Lee, Minseok Kwak, Junghwan Oh, Jun-O Jin

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
8.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 68 citations in OpenAlex.

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  7. Evaluation of MScientific reports · 2022
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  14. Progress of Phototherapy Applications in the Treatment of Bone Cancer.International journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Bian JangShanghai Public Health Clinical Center, Shanghai Medical College, Fudan University, Jinshan District, Shanghai, China.
Madhappan Santha MoorthyMarine-Integrated Bionics Research Center, Pukyong National University, Busan, South Korea.
Panchanathan ManivasaganMarine-Integrated Bionics Research Center, Pukyong National University, Busan, South Korea.
Li XuShanghai Public Health Clinical Center, Shanghai Medical College, Fudan University, Jinshan District, Shanghai, China.
Kyeongeun SongShanghai Public Health Clinical Center, Shanghai Medical College, Fudan University, Jinshan District, Shanghai, China.
Kang Dae LeeDepartment of Otolaryngology-Head and Neck Surgery, Kosin University College of Medicine, Busan, Korea.
Minseok KwakMarine-Integrated Bionics Research Center, Pukyong National University, Busan, South Korea.
Junghwan OhMarine-Integrated Bionics Research Center, Pukyong National University, Busan, South Korea.
Jun-O JinShanghai Public Health Clinical Center, Shanghai Medical College, Fudan University, Jinshan District, Shanghai, China.
Pukyong National University · KRShanghai Public Health Clinical Center · CNKosin University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In advanced cancer therapy, the combinational therapeutic effect of photothermal therapy (PTT) using near-infrared (NIR) light-responsive nanoparticles (NPs) and anti-cancer drug delivery-mediated chemotherapy has been widely applied. In the present study, using a facile, low-cost, and solution-based method, we developed and synthesized fucoidan, a natural polymer isolated from seaweed that has demonstrated anti-cancer effect, and coated NPs with it as an ideal candidate in chemo-photothermal therapy against cancer cells. Fucoidan-coated copper sulfide nanoparticles (F-CuS) act not only as a nanocarrier to enhance the intracellular delivery of fucoidan but also as a photothermal agent to effectively ablate different cancer cells (e.g., HeLa, A549, and K562), both

Indexed as

apoptosischemotherapycopper sulfide nanoparticlesfucodianphotothermal therapy

Identifiers

PMID29560098
PMCPMC5849162
OpenAlexW2781947239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.