Evidence map›Paper›PMID 29559930›Full record

ArticleFrontiers in psychiatry2018

Working Memory Modulates Glutamate Levels in the Dorsolateral Prefrontal Cortex during

Eric A Woodcock, Chaitali Anand, Dalal Khatib, Vaibhav A Diwadkar, Jeffrey A Stanley

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  7. Disentangling metabolic and neurovascular timescales supporting cognitive processes.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  8. Beyond Latency: ChronicBiomedicines · 2025
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  16. Human brain functional MRS reveals interplay of metabolites implicated in neurotransmission and neuroenergetics.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Eric A WoodcockBrain Imaging Research Division, Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, United States.
Chaitali AnandBrain Imaging Research Division, Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, United States.
Dalal KhatibBrain Imaging Research Division, Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, United States.
Vaibhav A DiwadkarBrain Imaging Research Division, Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, United States.
Jeffrey A StanleyBrain Imaging Research Division, Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, United States.
Wayne State University · US

Funding

Advancing innovative brain imaging to detect altered glutamate modulation and network dynamics in schizophreniaR01MH111177 · NIMH · WAYNE STATE UNIVERSITY · PI DIWADKAR, VAIBHAV A., STANLEY, JEFFREY A · 2016 to 2020
$2.9M
Neuropharmacological investigation of frontostriatal network function and nicotine seeking behavior in current smokersF31DA040369 · NIDA · WAYNE STATE UNIVERSITY · PI WOODCOCK, ERIC ANDREW · 2016 to 2017
$61k
NIDA NIH HHS F31 DA040369NIMH NIH HHS R01 MH111177
6 · The paper itself

Abstract

Glutamate is involved in excitatory neurotransmission and metabolic processes related to brain function. Previous studies using proton functional magnetic resonance spectroscopy (

Indexed as

dorsolateral prefrontal cortexexcitatory neurotransmissionglutamatemagnetic resonance spectroscopymetabolismneuroimagingworking memory

Identifiers

PMID29559930
PMCPMC5845718
OpenAlexW2793324766

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.