Evidence map›Paper›PMID 29559844›Full record

ArticleInternational journal of biological sciences2018

Instillation of particulate matter 2.5 induced acute lung injury and attenuated the injury recovery in ACE2 knockout mice.

Chung-I Lin, Chin-Hung Tsai, Yu-Ling Sun, Wen-Yeh Hsieh, Yi-Chang Lin, Cheng-Yi Chen, Chih-Sheng Lin

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 2 pooled it
16.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 2 syntheses or guidelines pooled it, 171 citations in OpenAlex.

  1. Impact of air pollution on COVID-19 severity: a systematic review of underlying biological mechanisms.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Chitosan Nanoparticle-EncapsulatedInternational journal of molecular sciences · 2025
    Article
  6. Observational
  7. Review
  8. PMToxics · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. ACE2: the node connecting the lung cancer and COVID-19.American journal of cancer research · 2024
    Review
  13. Article
  14. Carbon dioxide and MAPK signalling: towards therapy for inflammation.Cell communication and signaling : CCS · 2023
    Review
  15. Medicina (Kaunas, Lithuania) · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Air pollution and respiratory infections: the past, present, and future.Toxicological sciences : an official journal of the Society of Toxicology · 2023
    Review

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Chung-I LinDepartment of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan.
Chin-Hung TsaiDepartment of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan.
Yu-Ling SunAquatic Technology Laboratories, Agricultural Technology Research Institute, Hsinchu, Taiwan.
Wen-Yeh HsiehDivision of Chest Medicine, Department of Internal Medicine, Hsinchu Mackay Memorial Hospital, Hsinchu, Taiwan.
Yi-Chang LinDepartment of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan.
Cheng-Yi ChenDepartment of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan.
Chih-Sheng LinDepartment of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan.
Food Industry Research and Development Institute · TWMackay Memorial Hospital · TWAgricultural Technology Research Institute · TWNational Yang Ming Chiao Tung University · TWTungs' Taichung MetroHarbor Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhaled particulate matter 2.5 (PM

Indexed as

Acute Lung InjuryAngiotensin-Converting Enzyme 2AnimalsCytokinesGelatinasesInflammation MediatorsLungMaleMAP Kinase Signaling SystemMatrix MetalloproteinasesMiceMice, Inbred C57BLMice, KnockoutParticulate MatterPeptidyl-Dipeptidase APhosphorylationAce2 protein, mouseAngiotensin-Converting Enzyme 2CytokinesGelatinasesInflammation MediatorsMatrix MetalloproteinasesParticulate MatterPeptidyl-Dipeptidase AStat3 protein, mouseSTAT3 Transcription Factoracute lung injuryangiotensin-converting enzyme IIinflammationparticulate matter 2.5renin-angiotensin system

Identifiers

PMID29559844
PMCPMC5859472
OpenAlexW2791708939

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.