ArticleClinical and experimental gastroenterology2018
Clinical and laboratory features of intestinal tuberculosis.
Article in Clinical and experimental gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Meta-analysis of diagnostic accuracy of nucleic acid amplification tests for abdominal tuberculosis.PloS one · 2023Pooled it
- Gastrointestinal tuberculosis: A systematic review of epidemiology, presentation, diagnosis and treatment.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology AssociationPooled it
- A Case of False-Negative Staining Findings of Intestinal Tuberculosis and Multiple Lymphadenopathy.Digestive diseases and sciences · 2026Article
- The Overlap Between Crohn's Disease and Intestinal Tuberculosis: A Never-Ending Story.Medicina (Kaunas, Lithuania) · 2026Review
- Asymptomatic intestinal tuberculosis of the terminal ileum diagnosed on colonoscopy: a case report and literature review.Journal of rural medicine : JRM · 2024Article
- Intestinal tuberculosis with small bowel stricture and hemorrhage as the predominant manifestation: Three case reports.World journal of gastrointestinal surgery · 2024Article
- Demographic, Clinical, Radiological, and Surgical Outcome of Patients with Intestinal Tuberculosis: A Single-Center Retrospective Study.Research and reports in tropical medicine · 2024Article
- Clinical manifestations and immune response to tuberculosis.World journal of microbiology & biotechnology · 2023Review
- Article
- Applying logistic LASSO regression for the diagnosis of atypical Crohn's disease.Scientific reports · 2022Article
- Recent advances in the diagnosis of intestinal tuberculosis.BMC gastroenterology · 2022Review
- Application value of tissue tuberculosis antigen combined with Xpert MTB/RIF detection in differential diagnoses of intestinal tuberculosis and Crohn's disease.BMC infectious diseases · 2021Article
- Article
- A Novel Clinical Radiomics Nomogram to Identify Crohn's Disease from Intestinal Tuberculosis.Journal of inflammation research · 2021Article
- Clinicopathological profile of gastrointestinal tuberculosis: a multinational ID-IRI study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020Article
- GeneXpert in stool: Diagnostic yield in Intestinal Tuberculosis.Journal of clinical tuberculosis and other mycobacterial diseases · 2019Article
- Analysis of Phenotypic Variables and Differentiation Between Untypical Crohn's Disease and Untypical Intestinal Tuberculosis.Digestive diseases and sciences · 2019Article
- Surgical management of abdominal tuberculosis: A prospective single-center study.Tzu chi medical journalArticle
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsAs increasing numbers of Crohn's disease (CD) cases are being recognized in India, so the differential diagnosis of CD and gastrointestinal tuberculosis (GITB) is becoming increasingly important. If patients are misdiagnosed with GITB, toxicity may result from unnecessary anti-TB therapy and treatment of the primary disease (ie, CD) gets delayed. We therefore aimed to assess the accuracy of various parameters that can be used to predict GITB diagnosis at index evaluation. MATERIALS AND
methodsThis was a prospective, unicentric, observational study carried out in the gastroenterology department of a tertiary care hospital between August 2011 and January 2013. Patients who presented to our hospital and were suspected of having GITB were included in our study. Patients were then followed up over a 6-month period. STATISTICAL ANALYSIS: Chi-square test was used to analyze the data.
resultsOf the 69 patients with GITB, 49 (71.01%) had thickening of the involved part of the colon and 33 (47.83%) had abdominal lymphadenopathy. The ileocecal valve was involved in 58 patients (84.05%) Histological detection of granulomas had 78.95% specificity, 36.23% sensitivity, and 51.40% accuracy. Tuberculosis polymerase chain reaction was found to have 78.95% specificity, 71.01% sensitivity, and 73.83% accuracy. BACTEC-MGIT culture was found to have 100% specificity, 20.29% sensitivity, and 48.60% accuracy.
conclusionAlthough histology is helpful in ruling out other conditions, TB-specific findings such as caseating granuloma and acid-fast bacilli are rarely seen. Instead, tuberculosis polymerase chain reaction has the highest diagnostic accuracy followed by BACTEC culture.
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