Evidence map›Paper›PMID 29559683›Full record

Trial reportSpinal cord2018

Plasma adiponectin levels are correlated with body composition, metabolic profiles, and mitochondrial markers in individuals with chronic spinal cord injury.

Laura C O'Brien, Zachary A Graham, Qun Chen, Edward J Lesnefsky, Christopher Cardozo, Ashraf S Gorgey

2 registry-linked trialsOpen access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Spinal cord, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01652040 phase2 / phase3completednot on this map

Effects of Evoked Resistance Training and Testosterone After Spinal Cord Injury

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2012 to 2017Enrolled26ConditionsSpinal Cord InjuryArmsResistance Training and Testosterone Patches, Testosterone Patches
NCT05997251 completednot on this mapstarted 2021, after this paper: background citation

The Relationship of DASH and Mediterranean Diet Score With Serum Adiponectin Levels in Patients With Spinal Cord Injury

TypeobservationalSponsorAnkara City Hospital BilkentRan2021 to 2022Enrolled66ConditionsSpinal Cord InjuriesArmsKeeping a 1-day food consumption record by the patient, Measurement of adiponectin level
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

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  8. Humanin and diabetes mellitus: A review ofWorld journal of diabetes · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Laura C O'BrienSpinal Cord Injury and Disorders, Hunter Holmes McGuire VA Medical Center, Richmond, VA, USA.
Zachary A GrahamDepartment of James J. Peters VA Medical Center, Bronx, NY, USA.ORCID http://orcid.org/0000-0002-6506-7025
Qun ChenDepartment of Medicine, Division of Cardiology, Pauley Heart Center, Virginia Commonwealth University, Richmond, VA, USA.
Edward J LesnefskyDepartment of Physiology and Biophysics, Virginia Commonwealth University, Richmond, VA, USA.
Christopher CardozoDepartment of James J. Peters VA Medical Center, Bronx, NY, USA.
Ashraf S GorgeySpinal Cord Injury and Disorders, Hunter Holmes McGuire VA Medical Center, Richmond, VA, USA. ashraf.gorgey@va.gov.ORCID http://orcid.org/0000-0002-9157-6034
Virginia Commonwealth University · USJames J. Peters VA Medical Center · USHunter Holmes McGuire VA Medical Center · US

Funding

Effects of Evoked Resistance Training and Testosterone after Spinal Cord InjuryIK2RX000732 · VA · VA VETERANS ADMINISTRATION HOSPITAL · PI GORGEY, ASHRAF · 2012 to 2016
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RRD VA IK2 RX000732
6 · The paper itself

Abstract

STUDY

designCross-sectional design.

objectivesThis study examined the relationships between circulating adiponectin levels, body composition, metabolic profile, and measures of skeletal muscle mitochondrial enzyme activity and biogenesis. SETTINGS: Clinical Research in a Medical Center.

methodsPlasma adiponectin was quantified in 19 individuals with chronic spinal cord injury (SCI). Body composition was evaluated by dual x-ray absorptiometry and magnetic resonance imaging. Metabolic profile was assessed by basal metabolic rate (BMR), oxygen uptake (VO

resultsAdiponectin was negatively related to both total and regional fat mass and positively related to lean mass and muscle mass. Furthermore, there were positive relationships between adiponectin and BMR (r = 0.52, P = 0.02) and VO

conclusionsThe study demonstrated that adiponectin is closely related to body composition and metabolic profile in persons with SCI and further supports mechanistic studies suggesting that adiponectin may stimulate mitochondrial biogenesis.

Indexed as

Body CompositionAbsorptiometry, PhotonAdenylate KinaseAdiponectinAdipose TissueAdolescentAdultChronic DiseaseCross-Sectional StudiesHumansMagnetic Resonance ImagingMaleMiddle AgedMitochondriaMuscle, SkeletalOrganelle BiogenesisAdenylate KinaseAdiponectinADIPOQ protein, humanPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPPARGC1A protein, human

Identifiers

PMID29559683
PMCPMC6129201
OpenAlexW2795523796

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.