Evidence map›Paper›PMID 29559568›Full record

ArticlemBio2018

TgTKL1 Is a Unique Plant-Like Nuclear Kinase That Plays an Essential Role in Acute Toxoplasmosis.

Joseph M Varberg, Isabelle Coppens, Gustavo Arrizabalaga, Rajshekhar Y Gaji

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Prophylactic Effect of Microwave Radiation onJournal of parasitology research · 2025
    Article
  5. Article
  6. TKL family kinases in human apicomplexan pathogens.Molecular and biochemical parasitology · 2024
    Review
  7. Article
  8. The Crk4-Cyc4 complex regulates GThe EMBO journal · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Protein kinases in Toxoplasma gondii.International journal for parasitology · 2021
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Joseph M VarbergDepartment of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Isabelle CoppensDepartment of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Gustavo ArrizabalagaDepartment of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Rajshekhar Y GajiDepartment of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA rgaji@iupui.edu.
Indiana University School of MedicineJohns Hopkins University · US

Funding

Dissecting the calcium dependent phosphorylation network of Toxoplasma gondiiR01AI123457 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI ARRIZABALAGA, GUSTAVO A, TREECK, MORITZ · 2016 to 2020
$2.7M
NIAID NIH HHS R01 AI123457
6 · The paper itself

Abstract

In the protozoan parasite

Indexed as

AnimalsFemaleMiceProtein-Tyrosine KinasesProtozoan ProteinsSignal TransductionToxoplasmaToxoplasmosisProtein-Tyrosine KinasesProtozoan Proteinsapicomplexan parasiteshost cell invasionkinaseToxoplasma gondii

Identifiers

PMID29559568
PMCPMC5874906
OpenAlexW2790611808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.