Evidence map›Paper›PMID 29559559›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2018

Anaplastic Lymphoma Kinase Mutation (

Benedito A Carneiro, Sahithi Pamarthy, Ami N Shah, Vinay Sagar, Kenji Unno, HuiYing Han, Ximing J Yang, Rubens B Costa, Rebecca J Nagy, Richard B Lanman and 9 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 1 country.

Benedito A Carneiro *Division of Hematology/Oncology, Lifespan Cancer Institute, the Warren Alpert Medical School, Brown University, Providence, Rhode Island. Benedito.carneiro@lifespan.org.
Sahithi Pamarthy *The Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois.ORCID 0000-0003-2692-4829
Ami N ShahDevelopmental Therapeutics Program, Division of Hematology/Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Vinay SagarThe Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois.ORCID 0000-0003-1717-742X
Kenji UnnoThe Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
HuiYing HanThe Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Ximing J YangDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Rubens B CostaDevelopmental Therapeutics Program, Division of Hematology/Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.ORCID 0000-0002-3492-4397
Rebecca J NagyGuardant Health, Inc., Redwood City, California.
Richard B LanmanGuardant Health, Inc., Redwood City, California.ORCID 0000-0001-8122-4329
Timothy M KuzelRush University Medical Center, Division of Hematology/Oncology, Chicago, Illinois.
Jeffrey S RossFoundation Medicine Inc., Cambridge, Massachusetts.
Laurie GayFoundation Medicine Inc., Cambridge, Massachusetts.
Julia A ElvinFoundation Medicine Inc., Cambridge, Massachusetts.
Siraj M AliFoundation Medicine Inc., Cambridge, Massachusetts.
Massimo CristofanilliThe Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Young K ChaeThe Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Francis J GilesDevelopmental Therapeutics Consortium, Chicago, Illinois.ORCID 0000-0002-6919-0231
Sarki A AbdulkadirThe Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Northwestern University · USGuardant (United States) · USBrown University · USMolecular Biology Consortium · USRobert H. Lurie Comprehensive Cancer Center of Northwestern UniversitySUNY Upstate Medical University · USUniversity of Chicago Medical Center · US

Funding

Targeting FOXA1-downstream pathways: a novel therapeutic strategy for castration-resistant prostate cancerP50CA180995 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ABDULKADIR, SARKI A., HUSSAIN, MAHA H · 2015 to 2025
$19.9M
Role of Oncogenic Kinase Pim-1 in Prostate CancerR01CA123484 · NCI · VANDERBILT UNIVERSITY · PI ABDULKADIR, SARKI A. · 2007 to 2017
$2.9M
Prostate Cancer Recurrence: models and mechanismsR01CA167966 · NCI · VANDERBILT UNIVERSITY · PI ABDULKADIR, SARKI A. · 2012 to 2016
$1.8M
NCI NIH HHS P50 CA180995NCI NIH HHS R01 CA123484NCI NIH HHS R01 CA167966
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MutationAdultAnaplastic Lymphoma KinaseBiomarkers, TumorCarbazolesCarcinoma, Small CellCell Line, TumorGene Expression ProfilingHigh-Throughput Nucleotide SequencingHumansImmunohistochemistryKaplan-Meier EstimateLiquid BiopsyMaleNeoplasm GradingNeoplasm MetastasisalectinibAnaplastic Lymphoma KinaseBiomarkers, TumorCarbazolesPiperidinesProtein Kinase Inhibitors

Identifiers

PMID29559559
PMCPMC6715284
OpenAlexW2793120694

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.