ArticleThe Journal of biological chemistry2018
Site-specific
Erratum issuedOpen access · hybridAbstract read
In one paragraph
Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 44 papers.
0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 80 citations in OpenAlex.
- The ligand preference of LRP1 is regulated by O-glycans.Science advances · 2026Article
- Integrative structural analysis of the human LRP2-LRPAP1 complex reveals multiple regulatory sites.Communications biology · 2026Article
- Pathways and Molecular Mechanisms Governing LDL Receptor Regulation.Circulation research · 2025Review
- Global characterization of mouse testis O-glycoproteome landscape during spermatogenesis.Nature communications · 2025Article
- Synergistic effects of mutation and glycosylation on disease progression.Frontiers in molecular biosciences · 2025Review
- Whole exome sequencing identifies concurrentFrontiers in genetics · 2025Article
- Rational Design of Dual-Domain Binding Inhibitors forJACS Au · 2024Article
- Cosmc regulates O-glycan extension in murine hepatocytes.Glycobiology · 2024Article
- Cryo-EM structures elucidate the multiligand receptor nature of megalin.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Sequential glycosylations at the multibasic cleavage site of SARS-CoV-2 spike protein regulate viral activity.Nature communications · 2024Article
- OptiMo-LDLr: An Integrated In Silico Model with Enhanced Predictive Power for LDL Receptor Variants, Unraveling Hot Spot Pathogenic Residues.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) isozyme surface charge governs charge substrate preferences to modulate mucin type O-glycosylation.Glycobiology · 2023Article
- Roles of protein post-translational modifications in glucose and lipid metabolism: mechanisms and perspectives.Molecular medicine (Cambridge, Mass.) · 2023Review
- Molecular Recognition of GalNAc in Mucin-Type O-Glycosylation.Accounts of chemical research · 2023Review
- Identification of global inhibitors of cellular glycosylation.Nature communications · 2023Article
- Article
- Global mapping of GalNAc-T isoform-specificities and O-glycosylation site-occupancy in a tissue-forming human cell line.Nature communications · 2022Article
- Article
- Thirty-Five-Year History of Desialylated Lipoproteins Discovered by Vladimir Tertov.Biomedicines · 2022Review
- Global Loss of Core 1-DerivedInternational journal of molecular sciences · 2022Article
Corrections and comments
- Erratum issuedSite-specific2019
Authors and funding
21 authors at 6 institutions in 3 countries.
Shengjun WangCopenhagen Center for Glycomics, Departments of Cellular and Molecular Medicine and School of Dentistry, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
Yang MaoCopenhagen Center for Glycomics, Departments of Cellular and Molecular Medicine and School of Dentistry, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
Yoshiki NarimatsuCopenhagen Center for Glycomics, Departments of Cellular and Molecular Medicine and School of Dentistry, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
Zilu YeCopenhagen Center for Glycomics, Departments of Cellular and Molecular Medicine and School of Dentistry, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
Weihua TianCopenhagen Center for Glycomics, Departments of Cellular and Molecular Medicine and School of Dentistry, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
Christoffer K GothCopenhagen Center for Glycomics, Departments of Cellular and Molecular Medicine and School of Dentistry, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
Erandi Lira-NavarreteCopenhagen Center for Glycomics, Departments of Cellular and Molecular Medicine and School of Dentistry, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
Nis B PedersenCopenhagen Center for Glycomics, Departments of Cellular and Molecular Medicine and School of Dentistry, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
Asier Benito-VicenteBiofisika Institute, Centro Superior de Investigaciones Cientificas (CSIC), Universidad del Pais Vasco/Euskal Herriko Unibertsitatea (UPV/EHU), and Departamento de Bioquimica, Universidad del Pais Vasco, 48080 Bilbao, Spain.
Cesar MartinBiofisika Institute, Centro Superior de Investigaciones Cientificas (CSIC), Universidad del Pais Vasco/Euskal Herriko Unibertsitatea (UPV/EHU), and Departamento de Bioquimica, Universidad del Pais Vasco, 48080 Bilbao, Spain.
Kepa B UribeBiofisika Institute, Centro Superior de Investigaciones Cientificas (CSIC), Universidad del Pais Vasco/Euskal Herriko Unibertsitatea (UPV/EHU), and Departamento de Bioquimica, Universidad del Pais Vasco, 48080 Bilbao, Spain.
Ramon Hurtado-GuerreroThe Institute for Biocomputation and Physics of Complex Systems (BIFI), University of Zaragoza, BIFI-Instituto de Química Física Rocasolano (IQFR), CSIC Joint Unit, Mariano Esquillor s/n, Campus Rio Ebro, 50009 Zaragoza, Spain.
Christina ChristoffersenDepartment of Clinical Biochemistry, Rigshospitalet and Department of Biomedical Sciences, University of Copenhagen, Copenhagen 2100, Denmark.
Nabil G SeidahClinical Research Institute of Montreal, University of Montreal, Montreal, Quebec H2W 1R7, Canada.
Rikke NielsenDepartment of Biomedicine, Aarhus University, DK-8000 Aarhus, Denmark.
Erik I ChristensenDepartment of Biomedicine, Aarhus University, DK-8000 Aarhus, Denmark.
Lars HansenCopenhagen Center for Glycomics, Departments of Cellular and Molecular Medicine and School of Dentistry, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
Eric P BennettCopenhagen Center for Glycomics, Departments of Cellular and Molecular Medicine and School of Dentistry, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
Sergey Y VakhrushevCopenhagen Center for Glycomics, Departments of Cellular and Molecular Medicine and School of Dentistry, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark.
Katrine T SchjoldagerCopenhagen Center for Glycomics, Departments of Cellular and Molecular Medicine and School of Dentistry, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark. Electronic address: schjoldager@sund.ku.dk.
Henrik ClausenCopenhagen Center for Glycomics, Departments of Cellular and Molecular Medicine and School of Dentistry, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen N, Denmark. Electronic address: hclau@sund.ku.dk.
University of Copenhagen · DKUniversity of the Basque Country · ESAarhus University · DKInstituto de Química Física Blas Cabrera · ESRigshospitalet · DKUniversité de Montréal · CA
Funding
No grant is acknowledged in the PubMed record.
Abstract
The low-density lipoprotein receptor (LDLR) and related receptors are important for the transport of diverse biomolecules across cell membranes and barriers. Their functions are especially relevant for cholesterol homeostasis and diseases, including neurodegenerative and kidney disorders. Members of the LDLR-related protein family share LDLR class A (LA) repeats providing binding properties for lipoproteins and other biomolecules. We previously demonstrated that short linker regions between these LA repeats contain conserved
Indexed as
AcetylgalactosamineAnimalsCell MembraneCHO CellsCricetulusDrosophilaGlycosylationHEK293 CellsHep G2 CellsHumansLigandsLipoproteinsLow Density Lipoprotein Receptor-Related Protein-1Low Density Lipoprotein Receptor-Related Protein-2PolysaccharidesProtein BindingAcetylgalactosamineLigandsLipoproteinsLow Density Lipoprotein Receptor-Related Protein-1Low Density Lipoprotein Receptor-Related Protein-2LRP1 protein, humanLRP2 protein, humanPolysaccharidesReceptors, LDLRecombinant ProteinsVLDL receptorGALNTglycosylationglycosyltransferaselipid metabolismlipophorin receptorlipoprotein receptorlow-density lipoprotein (LDL)O-glycosylation
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.