Evidence map›Paper›PMID 29559553›Full record

ArticleEndocrine-related cancer2018

A classification prognostic score to predict OS in stage IV well-differentiated neuroendocrine tumors.

Sara Pusceddu, Francesco Barretta, Annalisa Trama, Laura Botta, Massimo Milione, Roberto Buzzoni, Filippo De Braud, Vincenzo Mazzaferro, Ugo Pastorino, Ettore Seregni and 30 more

Abstract read
In one paragraph

Article in Endocrine-related cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. A tool to predict survival in stage IV entero-pancreatic NEN.Journal of endocrinological investigation · 2021
    Observational
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

40 authors.

Sara PuscedduDepartment of Medical Oncology ENETS Center of ExcellenceFondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy sara.pusceddu@istitutotumori.mi.it.
Francesco BarrettaUnit of Clinical Epidemiology and Trial OrganizationFondazione IRCCS Istituto Nazionale dei Tumori di Milano, ENETS Center of Excellence, Milan, Italy.
Annalisa TramaDepartment of Preventive and Predictive MedicineFondazione IRCCS Istituto Nazionale dei Tumori di Milano, Evaluative Epidemiology Unit, ENETS Center of Excellence, Milan, Italy.
Laura BottaDepartment of Preventive and Predictive MedicineFondazione IRCCS Istituto Nazionale dei Tumori di Milano, Evaluative Epidemiology Unit, ENETS Center of Excellence, Milan, Italy.
Massimo MilioneDepartment of PathologyFondazione IRCCS Istituto Nazionale dei Tumori, Milano, ENETS Center of Excellence, Milan, Italy.
Roberto BuzzoniDepartment of Medical Oncology ENETS Center of ExcellenceFondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.
Filippo De BraudDepartment of Medical Oncology ENETS Center of ExcellenceFondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.
Vincenzo MazzaferroUniversity of MilanMilan, Italy.
Ugo PastorinoDepartment of Thoracic Surgical OncologyFondazione IRCCS Istituto Nazionale dei Tumori, Milano, ENETS Center of Excellence, Milan, Italy.
Ettore SeregniDepartment of Nuclear Medicine ENETS Center of ExcellenceFondazione IRCCS Istituto Nazionale dei Tumori, Milano, Milan, Italy.
Luigi MarianiUnit of Clinical Epidemiology and Trial OrganizationFondazione IRCCS Istituto Nazionale dei Tumori di Milano, ENETS Center of Excellence, Milan, Italy.
Gemma GattaDepartment of Preventive and Predictive MedicineFondazione IRCCS Istituto Nazionale dei Tumori di Milano, Evaluative Epidemiology Unit, ENETS Center of Excellence, Milan, Italy.
Maria Di BartolomeoDepartment of Medical Oncology ENETS Center of ExcellenceFondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.
Daniela FemiaDepartment of Medical Oncology ENETS Center of ExcellenceFondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.
Natalie PrinziDepartment of Medical Oncology ENETS Center of ExcellenceFondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.
Jorgelina CoppaLiver SurgeryTransplantation and Gastroenterology, University of Milan and Istituto Nazionale Tumori Fondazione IRCCS, ENETS Center of Excellence, Milano, Milan, Italy.
Francesco PanzutoDepartment of Medical GastroenterologyAzienda Ospedaliera Sant'Andrea, Roma ENETS Center of Excellence, Rome, Italy.
Lorenzo AntonuzzoDepartment of Medical OncologyAzienda Ospedaliera Universitaria Careggi, Firenze, Italy.
Emilio BajettaDepartment of Medical OncologyPoliclinico di Monza, Monza, Italy.
Maria Pia BrizziDepartment of Medical OncologyAzienda Ospedaliera Universitaria San Luigi Gonzaga, Orbassano, Italy.
Davide CampanaDepartment of Medical OncologyPoliclinico Sant'Orsola Malpighi, Bologna, Italy.
Laura CatenaDepartment of Medical OncologyPoliclinico di Monza, Monza, Italy.
Harry ComberIreland National Cancer RegistryCork, Ireland.
Fiona DwaneIreland National Cancer RegistryCork, Ireland.
Nicola FazioDepartment of Medical OncologyIEO - Istituto Europeo di Oncologia, Milano, ENETS Center of Excellence, Milan, Italy.
Antongiulio FaggianoDepartment of Thyroid and Parathyroid Surgery UnitAzienda Ospedaliera Universitaria Federico II, ENETS Center of Excellence, Naples, Italy.
Dario GiuffridaDepartment of Medical OncologyIOM - Istituto Oncologico del Mediterraneo, Catania, Italy.
Kris HenauBelgian Cancer RegistryBrussels, Belgium.
Toni IbrahimOsteoncology and Rare Tumors CenterIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori IRST, IRCCS, Meldola, Italy.
Riccardo MarconciniDepartment of Medical OncologyOspedale Santa Chiara, Pisa, Italy.
Sara MassironiGastroenterology and Endoscopy UnitFondazione IRCCS Ospedale Maggiore Policlinico, Milan, Italy.
Maja Primic ŽakeljInstitute of Oncology LjubljanaEpidemiology and Cancer Registry, Ljubljana, Slovenia.
Francesca SpadaDepartment of Medical OncologyIEO - Istituto Europeo di Oncologia, Milano, ENETS Center of Excellence, Milan, Italy.
Salvatore TafutoDepartment of Medical OncologyFondazione IRCCS Pascale, ENETS Center of Excellence, Naples, Italy.
Elizabeth Van EyckenBelgian Cancer RegistryBrussels, Belgium.
Jan Maaten Van der ZwanDepartment of ResearchNetherlands Comprehensive Cancer Organisation (IKNL), Utrecht, The Netherlands.
Tina ŽagarInstitute of Oncology LjubljanaEpidemiology and Cancer Registry, Ljubljana, Slovenia.
Luca GiacomelliDepartment of Surgical Sciences and Integrated DiagnosticsUniversity of Genoa, Genoa, Italy.
Rosalba MiceliUnit of Clinical Epidemiology and Trial OrganizationFondazione IRCCS Istituto Nazionale dei Tumori di Milano, ENETS Center of Excellence, Milan, Italy.
NEPscore Working Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

No validated prognostic tool is available for predicting overall survival (OS) of patients with well-differentiated neuroendocrine tumors (WDNETs). This study, conducted in three independent cohorts of patients from five different European countries, aimed to develop and validate a classification prognostic score for OS in patients with stage IV WDNETs. We retrospectively collected data on 1387 patients: (i) patients treated at the Istituto Nazionale Tumori (Milan, Italy;

Indexed as

AgedFemaleHumansMaleMiddle AgedNeoplasm StagingNeuroendocrine TumorsPrognosisSeverity of Illness IndexSurvival Analysisneuroendocrine tumorsoverall survivalprognosisprognostic scorevalidation

Identifiers

PMID29559553
PMCPMC5920017

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.