Evidence map›Paper›PMID 29559450›Full record

ReviewDiabetes care2018

Current Challenges and Opportunities in the Prevention and Management of Diabetic Foot Ulcers.

William J Jeffcoate, Loretta Vileikyte, Edward J Boyko, David G Armstrong, Andrew J M Boulton

4 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Diabetes care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 176 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
176citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04137328 naunknown statusstarted 2019, after this paper: background citation

Clinical Study on the Improvement of Diabetic Neuropathic Pain by Liraglutide

Ran2019Enrolled60Registered outcomes3Posted comparisons0ConditionsDiabetic Neuropathic PainArmsInsulin, liraglutide
PMID 27186361PMID 29110715PMID 20359765PMID 24936731PMID 26813032PMID 28456941PMID 28608285PMID 29416128PMID 30320508other papers from this trial
Open the trial in the graph
NCT04395521 nacompletednot on this mapstarted 2021, after this paper: background citation

A Facebook Group-based Program for Foot Self-management Support of Adults With Diabetes Mellitus: A Feasibility Study in Canada

TypeinterventionalSponsorHelen ObilorRan2021 to 2021Enrolled32ConditionsDiabetic Foot UlcerArmsDiabetic foot self-management support
NCT04624516 nacompletednot on this mapstarted 2019, after this paper: background citation

Effect of Self-structured Foot Exercise on the Incidence of Plantar Foot Diabetic Ulcer Recurrence Post Healing at Least One Month

TypeinterventionalSponsorMaria SuryaniRan2019 to 2020Enrolled50ConditionsDiabetic Foot Ulcer, Diabetic FootArmsself-structured foot exercise
NCT05039645 nacompletednot on this mapstarted 2022, after this paper: background citation

A Pilot Study to Investigate the Use of Remote Thermovisual Monitoring in Patients With a Previous Diabetic Foot Ulcer, During the COVID-19 Pandemic.

TypeinterventionalSponsorBluedrop Medical LimitedRan2022 to 2023Enrolled31ConditionsDiabetic Foot UlcerArmsPatient specific, clinician determined Intervention
3 · Its place in the literature

Who cites it

176 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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  6. Nutritional interventions for treating foot ulcers in people with diabetes.The Cochrane database of systematic reviews · 2020
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116 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

William J JeffcoateDepartment of Diabetes and Endocrinology, Nottingham University Hospitals Trust, Nottingham, U.K. william.jeffcoate@gmail.com.ORCID 0000-0002-1744-7576
Loretta VileikyteDivision of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, U.K., and Diabetes Research Institute, Miller School of Medicine, University of Miami, Miami, FL.
Edward J BoykoVA Puget Sound Health Care System, Seattle, WA.ORCID 0000-0002-3695-192X
David G ArmstrongSouthwestern Academic Limb Salvage Alliance (SALSA), Department of Surgery, Keck School of Medicine of University of Southern California, Los Angeles, CA.
Andrew J M BoultonDivision of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, U.K., and Diabetes Research Institute, Miller School of Medicine, University of Miami, Miami, FL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic foot ulcers remain a major health care problem. They are common, result in considerable suffering, frequently recur, and are associated with high mortality, as well as considerable health care costs. While national and international guidance exists, the evidence base for much of routine clinical care is thin. It follows that many aspects of the structure and delivery of care are susceptible to the beliefs and opinion of individuals. It is probable that this contributes to the geographic variation in outcome that has been documented in a number of countries. This article considers these issues in depth and emphasizes the urgent need to improve the design and conduct of clinical trials in this field, as well as to undertake systematic comparison of the results of routine care in different health economies. There is strong suggestive evidence to indicate that appropriate changes in the relevant care pathways can result in a prompt improvement in clinical outcomes.

Indexed as

Critical PathwaysDelivery of Health CareDiabetic FootGeographyHealth Care CostsHumansIncidencePreventive MedicineQuality ImprovementTreatment Outcome

Identifiers

PMID29559450

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.