ArticlePloS one2018
Impact of comorbidities on the prognoses of trauma patients: Analysis of a hospital-based trauma registry database.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association of Tranexamic Acid Administration With Mortality and Thromboembolic Events in Patients With Traumatic Injury: A Systematic Review and Meta-analysis.JAMA network open · 2022Pooled it
- Machine learning models for early mortality prediction in trauma patients using public data: a nationwide retrospective study.World journal of emergency surgery : WJES · 2026Article
- Comorbidity Burden and Acute-Care Utilization in Adult Trauma Patients Across the Injury Severity Spectrum in a Nationwide Community-Based Survey (Korea, 2019-2023).Healthcare (Basel, Switzerland) · 2026Article
- Article
- Bimodal, But Not the Same: Persistent Late Peaks in Trauma Mortality.World journal of surgery · 2025Article
- Major trauma and comorbidity: a scoping review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Article
- Sepsis after trauma-evolving paradigms in stress biology and host response failure.Burns & trauma · 2025Review
- Discriminative Ability of the Charlson Comorbidity Index for Long-Term Mortality in a General Population: Nationwide, Population-Based Study of 10 Million Adults in Sweden.Clinical epidemiology · 2025Article
- ASA-score is associated with 90-day mortality after complicated mild traumatic brain injury - a retrospective cohort study.Acta neurochirurgica · 2024Article
- Trauma patients with metastatic cancer undergoing emergent surgery: A matched cohort analysis.Surgery open science · 2024Article
- Role of the Stress Index in Predicting Mortality among Patients with Traumatic Femoral Fractures.Diagnostics (Basel, Switzerland) · 2024Article
- Using Partnerships and Multiple Data Sources to Surveil Agricultural Injuries: Considerations and Recommendations.Journal of agromedicine · 2024Article
- Intramural Healthcare Consumption and Costs After Traumatic Brain Injury: A Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Study.Journal of neurotrauma · 2023Observational
- The effects of sex and neuter status on trauma survival in dogs: A Veterinary Committee on Trauma registry study.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) · 2022Article
- Opportunities to Improve Palliative Care Delivery in Trauma Critical Illness.The American journal of hospice & palliative care · 2022Article
- Long-term experience with a collagen-elastin scaffold in combination with split-thickness skin grafts for the treatment of full-thickness soft tissue defects: improvements in outcome-a retrospective cohort study and case report.Langenbeck's archives of surgery · 2022Article
- Evaluating the outcomes of blunt thoracic trauma in elderly patients following a fall from a ground level: higher level care institution vs. lower level care institution.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2021Observational
- ΔMST and the Regulation of Cardiac CSE and OTR Expression in Trauma and Hemorrhage.Antioxidants (Basel, Switzerland) · 2021Article
- The Interaction of the Endogenous Hydrogen Sulfide and Oxytocin Systems in Fluid Regulation and the Cardiovascular System.Antioxidants (Basel, Switzerland) · 2020Article
- Geriatric Trauma - A Rising Tide. Assessing Patient Safety Challenges in a Vulnerable Population Using Norwegian Trauma Registry Data and Focus Group Interviews: Protocol for a Mixed Methods Study.JMIR research protocols · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Here we conducted a retrospective analysis of hospital-based trauma registry database for evaluating the impacts of comorbidities on the prognosis for traumatized patients using Index of Coexistent Comorbidity Disease (ICED) scores. We analyzed the data of patients with blunt trauma who visited emergency department between January 1, 2011, and December 31, 2015 in Chang-Gung Memorial Hospital, Keelung branch, a single level I trauma center in the Northern Taiwan. All consecutive patients with blunt trauma who admitted to the intensive care unit or ordinary ward after initial managements in the emergency department were included. We measured the hospital mortality of blunt traumatized patients using alive discharge as a competing risk. To investigate conditional independence of mortality and ICED scores given Injury Severity Score (ISS), we used log-linear models for modeling independence structures. Overall, we included 4997 patients (median age [IQR], 59 years old (44-75 years); 55.3% male). The mortality rate of blunt traumatized patients was higher in the higher ICED scores group compared to lower ICED scores group (4.7% vs 1.8%, p < 0.001). Meanwhile, the higher ICED scores group were associated with older age, higher ISS, and longer hospital stay than lower ICED scores group. Higher ICED group had higher probability of transition-to-death and lower probability of transition-to-discharge under the competing risk model. In the multivariable analysis of transition-specific Cox models, higher ICED group were associated with higher risk for hospital mortality compared to lower ICED group (HR 1.60; [95% CI 1.04-2.47]; p = 0.032). Also, higher ICED group were associated with lower probability of transition-to-discharge (HR 0.79; [95%CI 0.73-0.86]; p < 0.001). Additionally, higher ICED scores accounted for hospital mortality among patients with ISS < 25. In conclusion, our study suggested that severity of comorbidity was associated with higher hospital mortality among traumatized patients, particularly lower ISS.
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