ArticlePloS one2018
The associations between plasma phytoestrogens concentration and metabolic syndrome risks in Chinese population.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Dietary polyphenols and the risk of metabolic syndrome: a systematic review and meta-analysis.BMC endocrine disorders · 2024Pooled it
- Comparing the effect of face-to-face and virtual education educational intervention on phytoestrogen consumption and menopausal symptoms in middle-aged women.Journal of education and health promotion · 2025Article
- Effect of Fermented Soy Beverage on Equol Production by Fecal Microbiota.Foods (Basel, Switzerland) · 2024Article
- Coumestrol induces oxidative stress and impairs migration and embryonic growth.Reproduction (Cambridge, England) · 2023Article
- Next generation risk assessment of human exposure to estrogens using safe comparator compound values based on in vitro bioactivity assays.Archives of toxicology · 2023Article
- Urinary phytoestrogens and the risk of uterine leiomyomata in US women.BMC women's health · 2023Article
- Phytoestrogens and Health Effects.Nutrients · 2023Review
- In Vitro and In Vivo Assessments of Anti-Hyperglycemic Properties of Soybean Residue Fermented withLife (Basel, Switzerland) · 2022Article
- Lignan exposure: a worldwide perspective.European journal of nutrition · 2022Review
- Opposing effects of S-equol supplementation on metabolic and behavioral parameters in mice fed a high-fat diet.Nutrition research (New York, N.Y.) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolic syndrome (MetS) has become an important issue in the healthcare systems of both developed and developing countries. Phytoestrogens have shown estrogenic effects, which may involve in the etiology of MetS. The current study consisted of 293 MetS cases and 264 healthy controls. The concentrations of seven plasma phytoestrogens (daidzein, genistein, glycitein, equol, enterolactone, enterodiol and coumestrol) were detected by UPLC-MS/MS. Adjusted unconditional logistic regression was used to assess the associations between plasma phytoestrogens concentration and risks of MetS, as well as the associations between plasma phytoestrogens concentration and MetS components. Linear regression was used to evaluate the associations between equol concentration in equol-producers and MetS components. Higher concentrations of total isoflavone and equol were associated with decreased risk of MetS. The equol concentration was negatively associated with waist circumference and positively associated with HDL-C level. Increased daidzein was associated with both lower waist circumference and lower fasting blood glucose levels. Our results suggested that higher plasma total isoflavone, equol and daidzein might decrease MetS risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.