Trial reportNutrients2018
Effects of Different Dietary and Lifestyle Modification Therapies on Metabolic Syndrome in Prediabetic Arab Patients: A 12-Month Longitudinal Study.
Trial report in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06813131 (The Effect of Medical Nutrition Therapy and Follow-Up Frequency on Parameters Related to Metabolic Syndrome in Individuals With Metabolic Syndrome), which is not on this map. Cited by 31 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Medical Nutrition Therapy and Follow-Up Frequency on Parameters Related to Metabolic Syndrome in Individuals With Metabolic Syndrome: A Randomized Controlled Trial
Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- The Effects of Diverse Interventions on Diabetes Management Among Arabs With Diabetes: A Systematic Review.Journal of advanced nursing · 2025Pooled it
- Pooled it
- Metformin for prevention or delay of type 2 diabetes mellitus and its associated complications in persons at increased risk for the development of type 2 diabetes mellitus.The Cochrane database of systematic reviews · 2019 · on this mapPooled it
- Effect of therapeutic lifestyle change on metabolic syndrome in adults: a randomized controlled trial.Scientific reports · 2025Trial
- Efficacy of lifestyle intervention program for Arab women with prediabetes using social media as an alternative platform of delivery.Journal of diabetes investigation · 2021Trial
- Effects of A 12-Month Intensive Lifestyle Monitoring Program in Predominantly Overweight/Obese Arab Adults with Prediabetes.Nutrients · 2020Trial
- Improvements in Glycemic, Micronutrient, and Mineral Indices in Arab Adults with Pre-Diabetes Post-Lifestyle Modification Program.Nutrients · 2019Trial
- Efficacy and safety of anti-prediabetic drugs in patients with prediabetes: a Bayesian network meta-analysis.BMC medicine · 2026Article
- Challenges in child and adolescent health across the Arab Gulf countries-Focus on metabolic health.Clinical obesity · 2025Review
- A Holistic Approach to Metabolic Health Assessment-Analysis of Bioimpedance, Blood, and Saliva Biochemistry in Population Studies-A Pilot Study.Metabolites · 2025Article
- Lifestyle Modification Programs and Interventions on Prediabetes in Saudi Arabia: A Systematic Scoping Review.Journal of prevention (2022) · 2025Article
- Molecular mechanisms and treatment strategies for estrogen deficiency-related and glucocorticoid-induced osteoporosis: a comprehensive review.Inflammopharmacology · 2025Review
- Effectiveness of an educational intervention on the components of the metabolic syndrome of adults with type 2 diabetes: non-randomized clinical trial.Investigacion y educacion en enfermeria · 2025Article
- Sex-specific effects of tea consumption and salt intake on metabolic syndrome and its components among oilfield workers.Frontiers in nutrition · 2025Article
- Trends and characteristics of the metabolically healthy obese phenotype in an Arab population.Frontiers in public health · 2024Article
- Prevalence and correlates of metabolic syndrome among women living in urban slums, Mysore, India.PLOS global public health · 2023Article
- Awareness, Knowledge and Attitude towards 'Superfood' Kale and Its Health Benefits among Arab Adults.Nutrients · 2022Article
- Cardiometabolic Effects of a 12-Month, COVID-19 Lockdown-Interrupted Lifestyle Education Program for Arab Adolescents.Frontiers in pediatrics · 2022Article
- Assessment of factors influencing the contribution of primary healthcare physicians in prevention of type 2 diabetes in South of Saudi Arabia.Journal of family medicine and primary care · 2021Article
- Long-Term Weight Loss Strategies for Obesity.The Journal of clinical endocrinology and metabolism · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This three-arm, randomized, controlled study aimed to determine the differences in the effects of general advice (GA) on lifestyle change, intensive lifestyle modification programme (ILMP) and GA + metformin (GA + Met) in reducing the prevalence of full metabolic syndrome (MetS) in subjects with prediabetes; 294 Saudis with prediabetes (fasting glucose 5.6-6.9 mmol/L) were initially randomized, 263 completed 6 months and 237 completed 12 months. They were allocated into three groups: GA group which received a standard lifestyle change education; ILMP which followed a rigorous lifestyle modification support on diet and physical activity; and a GA + Met group. Anthropometric and biochemical estimations were measured. Full MetS (primary endpoint) and its components (secondary endpoint) were screened at baseline, 6 and 12 months. Full MetS in the ILMP group decreased by 26% (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.