Evidence map›Paper›PMID 29558385›Full record

ArticleAntioxidants (Basel, Switzerland)2018

Microbial Biotransformation of a Polyphenol-Rich Potato Extract Affects Antioxidant Capacity in a Simulated Gastrointestinal Model.

Joelle Khairallah, Shima Sadeghi Ekbatan, Kebba Sabally, Michèle M Iskandar, Raza Hussain, Atef Nassar, Lekha Sleno, Laetitia Rodes, Satya Prakash, Danielle J Donnelly and 1 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Joelle KhairallahSchool of Human Nutrition, McGill University, 21111 Lakeshore, Ste. Anne de Bellevue, QC H9X 3V9, Canada. joelle.khairallah@mail.mcgill.ca.
Shima Sadeghi EkbatanSchool of Human Nutrition, McGill University, 21111 Lakeshore, Ste. Anne de Bellevue, QC H9X 3V9, Canada. shima.sadeghi@mail.mcgill.ca.
Kebba SaballySchool of Human Nutrition, McGill University, 21111 Lakeshore, Ste. Anne de Bellevue, QC H9X 3V9, Canada. kebba.sabally@mcgill.ca.
Michèle M IskandarSchool of Human Nutrition, McGill University, 21111 Lakeshore, Ste. Anne de Bellevue, QC H9X 3V9, Canada. michele.iskandar@mail.mcgill.ca.
Raza HussainSchool of Human Nutrition, McGill University, 21111 Lakeshore, Ste. Anne de Bellevue, QC H9X 3V9, Canada. raza.hussain@mail.mcgill.ca.
Atef NassarSchool of Human Nutrition, McGill University, 21111 Lakeshore, Ste. Anne de Bellevue, QC H9X 3V9, Canada. atef.nassar@mail.mcgill.ca.ORCID 0000-0002-0394-1530
Lekha SlenoChemistry Department, University of Quebec at Montreal, 2101 rue Jeanne-Mance, Montreal, QC H2X 2J6, Canada. sleno.lekha@uqam.ca.
Laetitia RodesDepartment of Biomedical Engineering, Duff Medical Building, McGill University, 3775 Rue University, Montreal, QC H3A 2B4, Canada. laetitia.rodes@mail.mcgill.ca.
Satya PrakashDepartment of Biomedical Engineering, Duff Medical Building, McGill University, 3775 Rue University, Montreal, QC H3A 2B4, Canada. satya.prakash@mcgill.ca.
Danielle J DonnellyPlant Science Department, McGill University, 21111 Lakeshore, Ste. Anne de Bellevue, QC H9X 3V9, Canada. danielle.donnelly@mcgill.ca.ORCID 0000-0003-0278-2037
Stan KubowSchool of Human Nutrition, McGill University, 21111 Lakeshore, Ste. Anne de Bellevue, QC H9X 3V9, Canada. stan.kubow@mcgill.ca.ORCID 0000-0001-5831-9880
McGill University · CAUniversité du Québec à Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A multistage human gastrointestinal model was used to digest a polyphenol-rich potato extract containing chlorogenic acid, caffeic acid, ferulic acid, and rutin as the primary polyphenols, to assess for their microbial biotransformation and to measure changes in antioxidant capacity in up to 24 h of digestion. The biotransformation of polyphenols was assessed by liquid chromatography-mass spectrometry. Antioxidant capacity was measured by the ferric reducing antioxidant power (FRAP) assay. Among the colonic reactors, parent (poly)phenols were detected in the ascending (AC), but not the transverse (TC) or descending (DC) colons. The most abundant microbial phenolic metabolites in all colonic reactors included derivatives of propionic acid, acetic acid, and benzoic acid. As compared to the baseline, an earlier increase in antioxidant capacity (

Indexed as

antioxidantbiotransformationdigestiongastrointestinal modelphenolic metabolitespolyphenolspotatoSolanum tuberosum

Identifiers

PMID29558385
PMCPMC5874529
OpenAlexW2793065713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.