Evidence map›Paper›PMID 29558382›Full record

ArticleMolecules (Basel, Switzerland)2018

Bridging from Brain to Tumor Imaging: (S)-(-)- and (R)-(+)-[

Mathias Kranz, Ralf Bergmann, Torsten Kniess, Birgit Belter, Christin Neuber, Zhengxin Cai, Gang Deng, Steffen Fischer, Jiangbing Zhou, Yiyun Huang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. RSC medicinal chemistry · 2021
    Review
  4. Review
  5. Article
  6. Approaches to PET Imaging of Glioblastoma.Molecules (Basel, Switzerland) · 2020
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Mathias KranzDepartment of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, 04318 Leipzig, Germany. m.kranz@hzdr.de.ORCID 0000-0002-5641-7396
Ralf BergmannDepartment of Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, 01328 Dresden, Germany. r.bergmann@hzdr.de.
Torsten KniessDepartment of Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, 01328 Dresden, Germany. t.kniess@hzdr.de.ORCID 0000-0002-4107-3455
Birgit BelterDepartment of Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, 01328 Dresden, Germany. b.belter@hzdr.de.
Christin NeuberDepartment of Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, 01328 Dresden, Germany. c.neuber@hzdr.de.
Zhengxin CaiDepartment of Diagnostic Radiology, PET Center, Yale University School of Medicine, New Haven, CT 06519, USA. zhengxin.cai@yale.edu.
Gang DengDepartment of Neurosurgery and Biomedical Engineering, Yale University School of Medicine, New Haven, CT 06519, USA. gang.deng@yale.edu.
Steffen FischerDepartment of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, 04318 Leipzig, Germany. s.fischer@hzdr.de.
Jiangbing ZhouDepartment of Neurosurgery and Biomedical Engineering, Yale University School of Medicine, New Haven, CT 06519, USA. jiangbing.zhou@yale.edu.
Yiyun HuangDepartment of Diagnostic Radiology, PET Center, Yale University School of Medicine, New Haven, CT 06519, USA. henry.huang@yale.edu.ORCID 0000-0002-6757-3220
Peter BrustDepartment of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, 04318 Leipzig, Germany. p.brust@hzdr.de.ORCID 0000-0001-5555-7058
Winnie Deuther-ConradDepartment of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, 04318 Leipzig, Germany. w.deuther-conrad@hzdr.de.
Jens PietzschDepartment of Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, 01328 Dresden, Germany. j.pietzsch@hzdr.de.ORCID 0000-0002-1610-1493
Helmholtz-Zentrum Dresden-Rossendorf · DEYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sigma-1 receptors (Sig1R) are highly expressed in various human cancer cells and hence imaging of this target with positron emission tomography (PET) can contribute to a better understanding of tumor pathophysiology and support the development of antineoplastic drugs. Two Sig1R-specific radiolabeled enantiomers (

Indexed as

AnimalsBenzofuransBrainBrain NeoplasmsCell Line, TumorHumansMaleMice, NudePiperidinesPositron-Emission TomographyReceptors, sigmaSigma-1 ReceptorTomography, X-Ray Computed1'-benzyl-3-(2-fluoroethyl)-3H-spiro((2)benzofuran-1,4'-piperidine)BenzofuransPiperidinesReceptors, sigmaSigma-1 Receptor[18F]fluspidinecarcinomadedicated small animal PET/CTglioblastomamelanomasigma-1 receptor

Identifiers

PMID29558382
PMCPMC6017399
OpenAlexW2790988094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.