Evidence map›Paper›PMID 29557251›Full record

ArticleSurgical innovation2018

Patient-Reported Outcomes Are Associated With Enhanced Recovery Status in Patients With Bladder Cancer Undergoing Radical Cystectomy.

Janet Baack Kukreja, Qiuling Shi, Courtney M Chang, Mohamed A Seif, Brandon M Sterling, Ting-Yu Chen, Kelly M Creel, Ashish M Kamat, Colin P Dinney, Neema Navai and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical innovation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Profiling patient-reported symptom recovery from oesophagectomy for patients with oesophageal squamous cell carcinoma: a real-world longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Janet Baack Kukreja1 The University of Texas MD Anderson Cancer Center, Houston TX, USA.
Qiuling Shi1 The University of Texas MD Anderson Cancer Center, Houston TX, USA.
Courtney M Chang1 The University of Texas MD Anderson Cancer Center, Houston TX, USA.ORCID https://orcid.org/0000-0003-0040-9386
Mohamed A Seif1 The University of Texas MD Anderson Cancer Center, Houston TX, USA.
Brandon M Sterling1 The University of Texas MD Anderson Cancer Center, Houston TX, USA.
Ting-Yu Chen1 The University of Texas MD Anderson Cancer Center, Houston TX, USA.
Kelly M Creel1 The University of Texas MD Anderson Cancer Center, Houston TX, USA.
Ashish M Kamat1 The University of Texas MD Anderson Cancer Center, Houston TX, USA.
Colin P Dinney1 The University of Texas MD Anderson Cancer Center, Houston TX, USA.
Neema Navai1 The University of Texas MD Anderson Cancer Center, Houston TX, USA.
Jay B Shah1 The University of Texas MD Anderson Cancer Center, Houston TX, USA.
Xin Shelley Wang1 The University of Texas MD Anderson Cancer Center, Houston TX, USA.ORCID https://orcid.org/0000-0003-2348-8005
The University of Texas MD Anderson Cancer Center · US

Funding

Improving Recovery after Major Cancer Surgery using Patient-Reported OutcomesR01CA205146 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI WANG, XIN SHELLEY · 2016 to 2019
$2.6M
NCI NIH HHS R01 CA205146
6 · The paper itself

Abstract

backgroundBladder cancer is a disease of the elderly that is associated with high morbidity in those treated with radical cystectomy. In this observational study of patients with bladder cancer undergoing radical cystectomy, we analyzed and compared patient-reported outcomes from those treated with Enhanced Recovery After Surgery (ERAS) methods versus those who received traditional perioperative care.

methodsWe enrolled patients who underwent radical cystectomy at a high-volume tertiary care referral center from November 2013 to December 2016, when the ERAS concept was being introduced into postoperative care at our institution. Patients reported symptom outcomes using the MD Anderson Symptom Inventory preoperatively and on postoperative days 1 to 5. Mann-Whitney U tests were used to compare symptom burden between the ERAS and traditional-care groups. General linear mixed-effects models were used for longitudinal data; linear regression models were used for multivariable analysis.

resultsPatients (N = 383) reported dry mouth, disturbed sleep, drowsiness, fatigue, pain, and lack of appetite as the most severe symptoms. Compared with the traditional-care group, the ERAS group had significantly less pain (est. = -0.98, P = .005), drowsiness (est. = -0.91, P = .009), dry mouth (est. = -1.21, P = .002), disturbed sleep (est. = -0.97, P = .01), and interference with functioning (est. = -0.70, P = .022) (adjusted for age, sex, surgical technique, and neoadjuvant chemotherapy status).

conclusionsThese results suggest that ERAS practice significantly reduced immediate postoperative symptom burden in bladder cancer patients recovering from radical cystectomy, supporting the use of patient-reported symptom burden as an outcome measure in perioperative care.

Indexed as

CystectomyAdultAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleMiddle AgedPatient Reported Outcome MeasuresTreatment OutcomeUrinary Bladder Neoplasmsbladder cancercystectomyERASpatient-reported outcomes

Identifiers

PMID29557251
PMCPMC5995564
OpenAlexW2792709784

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.