Evidence map›Paper›PMID 29557239›Full record

ArticleThe Journal of international medical research2018

Role of quantitative analysis of T2 relaxation time in differentiating benign from malignant breast lesions.

Li Liu, Bo Yin, Kawai Shek, Daoying Geng, Yiping Lu, Jianbo Wen, Xinping Kuai, Weijun Peng

Abstract read
In one paragraph

Article in The Journal of international medical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Applications of TFrontiers in oncology · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Quantitative MR Imaging of the Breast.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. CellularInternational journal of molecular sciences · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Li Liu1 Department of Radiology, 162765 Fudan University Shanghai Cancer Centre, Shanghai, China; Department of Oncology , Shanghai Medical College, Fudan University, Shanghai, China.
Bo Yin2 Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China.
Kawai Shek3 Department of Radiology, Queen Elizabeth Hospital, Hong Kong.
Daoying Geng2 Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China.
Yiping Lu2 Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China.
Jianbo Wen2 Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China.
Xinping Kuai2 Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China.
Weijun Peng1 Department of Radiology, 162765 Fudan University Shanghai Cancer Centre, Shanghai, China; Department of Oncology , Shanghai Medical College, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective To investigate the role of quantitative analysis of T2 relaxation time in the magnetic resonance imaging (MRI) diagnosis of breast cancer. Methods The study enrolled patients with clinical breast masses who were examined using MRI at eight different echo times. The differences in T2 relaxation time of benign and malignant breast lesions were analysed. Results A total of 67 patients (67 breast lesions: 46 malignant, 21 benign) were examined. The mean ± SD T2 relaxation time was significantly lower in the 46 malignant lesions compared with the 21 benign lesions (82.69 ± 15.37 ms versus 95.48 ± 26.51 ms, respectively). The area under the curve was 0.731. Using 79.52 ms as the cut-off between benign and malignant breast lesions, a sensitivity of 85.7% and a specificity of 58.7% were obtained. Conclusions There was a significant difference in T2 relaxation time between benign and malignant breast lesions. The specificity of using T2 relaxation time alone for the differentiation of benign from malignant lesions was not high, but it could constitute a new adjunct in the MRI diagnosis of breast cancer.

Indexed as

Magnetic Resonance ImagingAdultAgedBreast NeoplasmsCarcinoma, Ductal, BreastDiagnosis, DifferentialFemaleHumansMiddle AgedBreast cancermagnetic resonance imaging (MRI)T2 relaxation time

Identifiers

PMID29557239
PMCPMC5991255

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.