Evidence map›Paper›PMID 29557084›Full record

ArticleInternational ophthalmology2019

Epithelial map-guided anterior stromal micropuncture for the treatment of recurrent corneal erosion syndrome.

Konstantinos Oikonomakis, Myrsini Petrelli, Aleksandra Petrovic, Konstantinos Andreanos, Konstantinos Droutsas, Ilias Georgalas, George Kymionis

Abstract readCase Reports
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In one paragraph

Article in International ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Transepithelial phototherapeutic keratectomy for treatment-resistant recurrent corneal erosion syndrome.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  3. Review
  4. Recurrent corneal erosion: a comprehensive review.Clinical ophthalmology (Auckland, N.Z.) · 2019
    Review
  5. Advancements in keratoplasty: Exploring newer techniques and imaging modalities for enhanced surgical outcomes.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Konstantinos Oikonomakis1st Department of Ophthalmology, University of Athens, General Hospital of Athens "G.Gennimatas", 154 Mesogion Av, 115 27, Athens, Greece. konoikonomakis@gmail.com.ORCID http://orcid.org/0000-0003-3957-0409
Myrsini Petrelli1st Department of Ophthalmology, University of Athens, General Hospital of Athens "G.Gennimatas", 154 Mesogion Av, 115 27, Athens, Greece.
Aleksandra PetrovicFaculty of Biology and Medicine, University of Lausanne, Foundation Asylum Des Aveugles Hospital Ophthalmic Jules-Gonin, 15 France Av, Lausanne, 1004, Switzerland.
Konstantinos Andreanos1st Department of Ophthalmology, University of Athens, General Hospital of Athens "G.Gennimatas", 154 Mesogion Av, 115 27, Athens, Greece.
Konstantinos Droutsas1st Department of Ophthalmology, University of Athens, General Hospital of Athens "G.Gennimatas", 154 Mesogion Av, 115 27, Athens, Greece.
Ilias Georgalas1st Department of Ophthalmology, University of Athens, General Hospital of Athens "G.Gennimatas", 154 Mesogion Av, 115 27, Athens, Greece.
George Kymionis1st Department of Ophthalmology, University of Athens, General Hospital of Athens "G.Gennimatas", 154 Mesogion Av, 115 27, Athens, Greece.
National and Kapodistrian University of Athens · GRFondation Asile des Aveugles · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo introduce the use of corneal epithelial mapping by anterior segment optical coherence tomography (AS-OCT) as an ancillary testing for the identification of areas of loose epithelial adherence in recurrent corneal erosion syndrome (RCES), and the subsequent treatment of the latter with anterior stromal puncture (ASP).

methodsFive patients were presented with RCES following traumatic corneal abrasions. Following resolution of acute episodes, AS-OCT epithelial mapping was performed revealing in all patients an area of increased epithelial thickness (hot spot) corresponding to the site of loose attachment of the epithelium to the epithelial basement membrane. ASP to the area of epithelial thickening, as delineated by the epithelial map, was performed.

resultsTo date, none of the patients has shown any signs of disease recurrence over a period ranging from 6 to 20 months following the application of epithelial map-guided ASP.

conclusionsAS-OCT epithelial mapping can reveal the exact area of loose epithelial adherence in RCES. Hence, epithelial mapping can delineate the target area for treatment with ASP and may decrease the high failure rates of ASP.

Indexed as

PuncturesAdultAnterior Eye SegmentCorneal Dystrophies, HereditaryCorneal StromaEpithelium, CornealFemaleHumansMaleMiddle AgedOphthalmologic Surgical ProceduresTomography, Optical CoherenceAnterior segment optical coherence tomography (AS-OCT)Anterior stromal puncture (ASP)Corneal epithelial mappingRecurrent corneal erosion syndrome (RCES)

Identifiers

PMID29557084
OpenAlexW2789947817

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.