Evidence map›Paper›PMID 29556903›Full record

Trial reportInternational urology and nephrology2018

Value of electronic alerts for acute kidney injury in high-risk wards: a pilot randomized controlled trial.

Yanhua Wu, Yuanhan Chen, Shaowen Li, Wei Dong, Huaban Liang, Miaoyi Deng, Yingnan Chen, Shixin Chen, Xinling Liang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in International urology and nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yanhua WuDivision of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106, Zhong Shan Road 2, Guangzhou City, 510080, Guangdong Province, China.
Yuanhan ChenDivision of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106, Zhong Shan Road 2, Guangzhou City, 510080, Guangdong Province, China. johnchen76@126.com.
Shaowen LiDivision of Information Management, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106, Zhong Shan Road 2, Guangzhou City, 510080, Guangdong Province, China.
Wei DongDivision of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106, Zhong Shan Road 2, Guangzhou City, 510080, Guangdong Province, China.
Huaban LiangDivision of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106, Zhong Shan Road 2, Guangzhou City, 510080, Guangdong Province, China.
Miaoyi DengDivision of Information Management, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106, Zhong Shan Road 2, Guangzhou City, 510080, Guangdong Province, China.
Yingnan ChenDivision of Information Management, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106, Zhong Shan Road 2, Guangzhou City, 510080, Guangdong Province, China.
Shixin ChenDivision of Preventive Medicine, School of Public Health, Guangzhou Medical University, 195, Dongfeng West Road, Guangzhou City, 510182, Guangdong Province, China.
Xinling LiangDivision of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106, Zhong Shan Road 2, Guangzhou City, 510080, Guangdong Province, China. xinlingliang_ggh@163.com.ORCID http://orcid.org/0000-0002-6764-9571

Funding

Science and Technology Program of Guangzhou, China 201604020037
6 · The paper itself

Abstract

purposeTo investigate the application value of "electronic alerts" ("e-alerts") for acute kidney injury (AKI) among high-risk wards of hospitals.

methodsA prospective, randomized, controlled study was conducted. We developed an e-alert system for AKI and ran the system in intensive care units and divisions focusing on cardiovascular disease. The e-alert system diagnosed AKI automatically based on serum creatinine levels. Patients were assigned randomly to an e-alert group (467 patients) or non-e-alert group (408 patients). Only the e-alert group could receive pop-up messages.

resultsThe sensitivity, specificity, Youden Index and accuracy of the AKI e-alert system were 99.8, 97.7, 97.5 and 98.1%, respectively. The prevalence of the diagnosis for AKI and expanded-AKI (AKI or multiple-organ failure) in the e-alert group was higher than that in the non-e-alert group (AKI 7.9 and 2.7%, P = 0.001; expanded-AKI 16.3 and 6.1%, P < 0.001). The prevalence of nephrology consultation in the e-alert group was higher than that in the non-e-alert group (9.0 and 3.7%, P = 0.001). There was no significant difference in the prevalence dialysis, rehabilitation of renal function or death in the two groups.

conclusionThe e-alert system described here was a reliable tool to make an accurate diagnosis of AKI.

Indexed as

AlgorithmsEarly DiagnosisIntensive Care UnitsRenal DialysisAcute Kidney InjuryAgedChinaClinical AlarmsDisease ProgressionFemaleFollow-Up StudiesHospital MortalityHumansMaleMiddle AgedPilot ProjectsAcute kidney injuryDiagnosise-alertInformation systemSurveillance

Identifiers

PMID29556903
PMCPMC6096658

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.