ArticleSocial psychiatry and psychiatric epidemiology2018
Adverse life outcomes associated with adolescent psychotic experiences and depressive symptoms.
Article in Social psychiatry and psychiatric epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.
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Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Factors Related to Placebo Response in Randomized, Double-Blind Clinical Trials of Antidepressants in Children and Adolescents: A Meta-regression Analysis.Clinical drug investigation · 2023Pooled it
- Unhealthy behaviors associated with mental health disorders: a systematic comparative review of diet quality, sedentary behavior, and cannabis and tobacco use.Frontiers in public health · 2023Pooled it
- Systematic Review and Meta-analysis: The Association Between Child and Adolescent Depression and Later Educational Attainment.Journal of the American Academy of Child and Adolescent Psychiatry · 2021Pooled it
- A Randomized, Double-Blind, Placebo-Controlled Trial of Vilazodone in Children and Adolescents with Major Depressive Disorder with Twenty-Six-Week Open-Label Follow-Up.Journal of child and adolescent psychopharmacology · 2020Trial
- Psychiatric and substance use disorder polygenic scores are associated with the exposome in youth.European child & adolescent psychiatry · 2026Article
- Developmental coupling between obsessive-compulsive symptoms and psychotic-like experiences in youth: a four-wave longitudinal study.Scientific reports · 2026Article
- Social Defeat and Psychosis in the United States: A Replication and Critical Reconceptualization.Schizophrenia bulletin · 2026Article
- Prevalence and associated risk factors of psychotic experiences in the general population during the COVID-19 pandemic: a systematic review and meta-analysis.Annals of general psychiatry · 2026Article
- Associations of dietary patterns and screen time with depressive symptoms among adolescents in Shandong Province, China.BMC public health · 2025Article
- Social media use, risk behavior engagement, and mental health among middle adolescents in the Caribbean.BMC public health · 2025Article
- Unlocking the potential of the 3-hydroxykynurenine/kynurenic acid ratio: a promising biomarker in adolescent major depressive disorder.European archives of psychiatry and clinical neuroscience · 2025Article
- Editorial: Markers of clinical significance and treatment-seeking of psychotic experiences in non-clinical populations: potential resilience & risk factors.Frontiers in psychiatry · 2025Article
- Treatment Options for Psychotic Depression in Adolescents: A Comprehensive Review.Psychology research and behavior management · 2025Review
- The association between sexual orientation and psychotic like experiences during adolescence: a prospective cohort study.Social psychiatry and psychiatric epidemiology · 2024Article
- Prevalence and risk factors of suicide attempts in young, first-episode and drug-naïve Chinese Han outpatients with psychotic major depressive disorder.European archives of psychiatry and clinical neuroscience · 2024Article
- Interaction effect of screen time and sugar-sweetened beverages with depressive symptoms in adolescents: evidence from a large sample-based survey in China.European child & adolescent psychiatry · 2024Article
- Psychotic symptoms in Chinese adolescent patients with major depressive disorder: prevalence and related endocrine clinical factors.BMC psychiatry · 2024Article
- Stress system concordance as a predictor of longitudinal patterns of resilience in adolescence.Development and psychopathology · 2023Article
- Educational attainment of adolescents treated in psychiatric inpatient care: a register study over 3 decades.European child & adolescent psychiatry · 2023Article
- Sleep disorders predict the 1-year onset, persistence, but not remission of psychotic experiences in preadolescence: a longitudinal analysis of the ABCD cohort data.European child & adolescent psychiatry · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
purposeTo investigate whether psychotic experiences and depressive symptoms at ages 12 and 18 years are associated with adverse life outcomes across a range of functional domains between 16 and 20 years of age.
methodsData were gathered from ALSPAC, a UK birth cohort. Individuals were assessed with the semi-structured Psychosis-Like Symptoms Interview and the Short Mood and Feeling Questionnaire at ages 12 and 18 years. Logistic regression was used to explore associations with outcomes in education, occupation, social functioning, substance use (alcohol, cannabis, smoking, and other drugs), and illegal behaviour between the ages of 16 and 20 years. All associations were adjusted for socio-demographic and childhood confounders and for comorbid psychotic experiences or depressive symptoms.
resultsPsychotic experiences and depression at age 12 were associated with poorer educational, occupational, and social outcomes between the ages of 16 and 20; these withstood adjustment for confounding. Depressive symptoms at age 12 were also associated with harmful drinking. Psychotic experiences and depression at age 18 were additionally associated with other forms of substance use and illegal behaviour. Comorbidity had little impact at age 12, but was associated with significantly worse educational, social, and substance use outcomes at age 18.
conclusionsAdolescent psychotic experiences and depression represent a risk marker for a number of later adverse outcomes, most consistently with education and employment, but also social impairment, harmful drinking, and substance use. This highlights the importance of recognizing adolescent psychopathology, so that support can be provided to try and minimize adverse outcomes.
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