Evidence map›Paper›PMID 29556492›Full record

ReviewFrontiers in public health2018

Vaccines Meet Big Data: State-of-the-Art and Future Prospects. From the Classical 3Is ("Isolate-Inactivate-Inject") Vaccinology 1.0 to Vaccinology 3.0, Vaccinomics, and Beyond: A Historical Overview.

Nicola Luigi Bragazzi, Vincenza Gianfredi, Milena Villarini, Roberto Rosselli, Ahmed Nasr, Amr Hussein, Mariano Martini, Masoud Behzadifar

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Recent Advances in Tick Antigen Discovery and Anti-Tick Vaccine Development.International journal of molecular sciences · 2023
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. The Vaccine-Hesitant Moment.The New England journal of medicine · 2022
    Review
  15. Vaccinomics to Design a Multi-Epitopes Vaccine forInternational journal of environmental research and public health · 2022
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Nicola Luigi BragazziDepartment of Health Sciences (DISSAL), School of Public Health, University of Genoa, Genoa, Italy.
Vincenza GianfrediDepartment of Experimental Medicine, Unit of Public Health, School of Specialization in Hygiene and Preventive Medicine, University of Perugia, Perugia, Italy.
Milena VillariniUnit of Public Health, Department of Pharmaceutical Science, University of Perugia, Perugia, Italy.
Roberto RosselliLocal Health Unit (LHU) ASL3 Genovese, Genoa, Italy.
Ahmed NasrDepartment of Medicine and Surgery, Pathology University Milan Bicocca, San Gerardo Hospital, Monza, Italy.
Amr HusseinMedical Faculty, University of Parma, Parma, Italy.
Mariano MartiniSection of History of Medicine and Ethics, Department of Health Sciences, University of Genoa, Genoa, Italy.
Masoud BehzadifarHealth Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran.
University of Genoa · ITUniversity of Perugia · ITIran University of Medical Sciences · IRUniversity of Milano-Bicocca · ITUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccines are public health interventions aimed at preventing infections-related mortality, morbidity, and disability. While vaccines have been successfully designed for those infectious diseases preventable by preexisting neutralizing specific antibodies, for other communicable diseases, additional immunological mechanisms should be elicited to achieve a full protection. "New vaccines" are particularly urgent in the nowadays society, in which economic growth, globalization, and immigration are leading to the emergence/reemergence of old and new infectious agents at the animal-human interface. Conventional vaccinology (the so-called "vaccinology 1.0") was officially born in 1796 thanks to the contribution of Edward Jenner. Entering the twenty-first century, vaccinology has shifted from a classical discipline in which serendipity and the Pasteurian principle of the three

Indexed as

Big DataeHealthhistory of vaccinologyomics disciplinesvaccineWeb 2.0

Identifiers

PMID29556492
PMCPMC5845111
OpenAlexW2789579930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.