Evidence map›Paper›PMID 29556454›Full record

ReviewJournal of bone oncology2018

Surgical thyroparathyroidectomy prevents progression of 5TGM1 murine multiple myeloma

Maurizio Zangari, Hanna Yoo, Ik Jae Shin, Donghoon Yoon, Larry J Suva

Open access · goldAbstract readReview
In one paragraph

Review in Journal of bone oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Maurizio ZangariUniversity of Arkansas for Medical Sciences, Myeloma Institute for Research and Therapy, 4301W Markham #816, Little Rock, AR 72205, USA.
Hanna YooUniversity of Arkansas for Medical Sciences, Myeloma Institute for Research and Therapy, 4301W Markham #816, Little Rock, AR 72205, USA.
Ik Jae ShinUniversity of Arkansas for Medical Sciences, Myeloma Institute for Research and Therapy, 4301W Markham #816, Little Rock, AR 72205, USA.
Donghoon YoonUniversity of Arkansas for Medical Sciences, Myeloma Institute for Research and Therapy, 4301W Markham #816, Little Rock, AR 72205, USA.
Larry J SuvaDepartment of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA.
University of Arkansas for Medical Sciences · USTexas A&M University · US

Funding

Breast Cancer Bone MetastasisR01CA166060 · NCI · UNIV OF ARKANSAS FOR MED SCIS · PI SUVA, LARRY J. · 2013 to 2017
$1.5M
NCI NIH HHS R01 CA166060
6 · The paper itself

Abstract

The 5TGM1 multiple myeloma transplanted C57BL6/KaLwRij model recapitulates many disease features including monoclonal paraprotein production as well as the development of osteolytic bone lesions. Since a significant association between serum parathyroid hormone PTH variations, bone anabolism and myeloma progression in patients receiving proteasome inhibitors exists, this study investigated the effect of the PTH axis on murine myeloma development

Identifiers

PMID29556454
PMCPMC5854927
OpenAlexW2791246929

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.