Evidence map›Paper›PMID 29556440›Full record

Review3 Biotech2018

Fish trypsins: potential applications in biomedicine and prospects for production.

Kristal Jesús-de la Cruz, Carlos Alfonso Álvarez-González, Emyr Peña, José Antonio Morales-Contreras, Ángela Ávila-Fernández

Open access · bronzeAbstract readReview
In one paragraph

Review in 3 Biotech, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Circular Valorization of Yellowfin Tuna (Molecules (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Review
  4. Crustacean Proteases and Their Application in Debridement.Tropical life sciences research · 2020
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Kristal Jesús-de la CruzLaboratorio de Acuacultura, DACBiol-UJAT, Carr. Villahermosa-Cárdenas Km 0.5, 86139 Villahermosa, Tabasco México.
Carlos Alfonso Álvarez-GonzálezLaboratorio de Acuacultura, DACBiol-UJAT, Carr. Villahermosa-Cárdenas Km 0.5, 86139 Villahermosa, Tabasco México.
Emyr PeñaLaboratorio de Acuacultura, DACBiol-UJAT, Carr. Villahermosa-Cárdenas Km 0.5, 86139 Villahermosa, Tabasco México.
José Antonio Morales-Contreras2Centro de Investigación, DACS-Universidad Juárez Autónoma de Tabasco, Av. Gregorio Méndez No. 2838-A. Col. Tamulté, 86150 Villahermosa, Tabasco México.
Ángela Ávila-Fernández2Centro de Investigación, DACS-Universidad Juárez Autónoma de Tabasco, Av. Gregorio Méndez No. 2838-A. Col. Tamulté, 86150 Villahermosa, Tabasco México.ORCID 0000-0001-6432-4715
Universidad Juárez Autónoma de Tabasco · MXVillahermosa Institute of Technology · MXConsejo Nacional de Ciencia y Tecnología · GT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In fishes, trypsins are adapted to different environmental conditions, and the biochemical and kinetic properties of a broad variety of native isoforms have been studied. Proteolytic enzymes remain in high demand in the detergent, food, and feed industries; however, our analysis of the literature showed that, in the last decade, some fish trypsins have been studied for the synthesis of industrial peptides and for specific biomedical uses as antipathogenic agents against viruses and bacteria, which have been recently patented. In addition, innovative strategies of trypsin administration have been studied to ensure that trypsins retain their properties until they exert their action. Biomedical uses require the production of high-quality enzymes. In this context, the production of recombinant trypsins is an alternative. For this purpose,

Indexed as

AquacultureFish trypsinsRecombinant enzymesTrypsin applicationsTrypsin structure

Identifiers

PMID29556440
PMCPMC5856729
OpenAlexW2789973894

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.