ArticlePilot and feasibility studies2018
Exoskeleton-assisted gait training to improve gait in individuals with spinal cord injury: a pilot randomized study.
Article in Pilot and feasibility studies, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03011099 (Improving Gait Performance in Individuals With Spinal Cord Injuries), which is not on this map. Cited by 28 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Improving Gait Performance in Individuals With Spinal Cord Injuries: an Intervention Using Robotic Exoskeletons
Who cites it
28 citing papers in PubMed, 5 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- A systematic review of the determinants of implementation of a locomotor training program using a powered exoskeleton for individuals with a spinal cord injury.Clinical rehabilitation · 2023Pooled it
- The efficacy of gait rehabilitations for the treatment of incomplete spinal cord injury: a systematic review and network meta-analysis.Journal of orthopaedic surgery and research · 2023Pooled it
- Wearable powered exoskeletons for gait training in tetraplegia: a systematic review on feasibility, safety and potential health benefits.Acta neurologica Belgica · 2022Pooled it
- Overground robotic training effects on walking and secondary health conditions in individuals with spinal cord injury: systematic review.Journal of neuroengineering and rehabilitation · 2022Pooled it
- Systematic review on wearable lower-limb exoskeletons for gait training in neuromuscular impairments.Journal of neuroengineering and rehabilitation · 2021Pooled it
- Exoskeletal-Assisted Walking During Acute Inpatient Rehabilitation Enhances Recovery for Persons with Spinal Cord Injury-A Pilot Randomized Controlled Trial.Journal of neurotrauma · 2024Trial
- Walking improvement in chronic incomplete spinal cord injury with exoskeleton robotic training (WISE): a randomized controlled trial.Spinal cord · 2022Trial
- Robotic Rehabilitation in Spinal Cord Injury: Neurophysiological Basis and Severity-Based Clinical Framework.Brain sciences · 2026Review
- Motor imagery BCI enables more practical and user-friendly exoskeleton control than smartwatch for users with spinal cord injury: a preliminary study.Journal of neuroengineering and rehabilitation · 2026Article
- Ninety-Seven Percent of Trials Investigating Robotic Interventions in Physiotherapy Contained Abstract Spin: A Meta-Research Review.Cochrane evidence synthesis and methods · 2026Review
- Priming with transcutaneous spinal direct current stimulation followed by robotic exoskeleton gait training in individuals with spinal cord injury: A case series.The journal of spinal cord medicine · 2025Article
- Lokomat-Assisted Robotic Rehabilitation in Spinal Cord Injury: A Biomechanical and Machine Learning Evaluation of Functional Symmetry and Predictive Factors.Bioengineering (Basel, Switzerland) · 2025Article
- Review
- Gaussian regressor-based adaptive control of exoskeleton joints in the presence of system uncertainty.Wearable technologies · 2025Article
- Immersive virtual reality for learning exoskeleton-like virtual walking: a feasibility study.Journal of neuroengineering and rehabilitation · 2024Article
- Robot-Assisted Gait Training in Individuals With Spinal Cord Injury: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Annals of rehabilitation medicine · 2024Article
- Center of Mass Estimation for Impaired Gait Assessment Using Inertial Measurement Units.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2024Article
- Intensity of overground robotic exoskeleton training in two persons with motor-complete tetraplegia: a case series.Spinal cord series and cases · 2023Article
- Gait Recovery in Spinal Cord Injury: A Systematic Review with Metanalysis Involving New Rehabilitative Technologies.Brain sciences · 2023Review
- A low-power ankle-foot prosthesis for push-off enhancement.Wearable technologies · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundRobotic wearable exoskeletons have been utilized as a gait training device in persons with spinal cord injury. This pilot study investigated the feasibility of offering exoskeleton-assisted gait training (EGT) on gait in individuals with incomplete spinal cord injury (iSCI) in preparation for a phase III RCT. The objective was to assess treatment reliability and potential efficacy of EGT and conventional physical therapy (CPT).
methodsForty-four individuals were screened, and 13 were eligible to participate in the study. Nine participants consented and were randomly assigned to receive either EGT or CPT with focus on gait. Subjects received EGT or CPT, five sessions a week (1 h/session daily) for 3 weeks. American Spinal Injury Association (ASIA) Lower Extremity Motor Score (LEMS), 10-Meter Walk Test (10MWT), 6-Minute Walk Test (6MWT), Timed Up and Go (TUG) test, and gait characteristics including stride and step length, cadence and stance, and swing phase durations were assessed at the pre- and immediate post- training. Mean difference estimates with 95% confidence intervals were used to analyze the differences.
resultsAfter training, improvement was observed in the 6MWT for the EGT group. The CPT group showed significant improvement in the TUG test. Both the EGT and the CPT groups showed significant increase in the right step length. EGT group also showed improvement in the stride length.
conclusionEGT could be applied to individuals with iSCI to facilitate gait recovery. The subjects were able to tolerate the treatment; however, exoskeleton size range may be a limiting factor in recruiting larger cohort of patients. Future studies with larger sample size are needed to investigate the effectiveness and efficacy of exoskeleton-assisted gait training as single gait training and combined with other gait training strategies.
trial registrationClinicaltrials.org, NCT03011099, retrospectively registered on January 3, 2017.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.