Evidence map›Paper›PMID 29556361›Full record

ArticleTheranostics2018

Targeting regenerative exosomes to myocardial infarction using cardiac homing peptide.

Adam Vandergriff, Ke Huang, Deliang Shen, Shiqi Hu, Michael Taylor Hensley, Thomas G Caranasos, Li Qian, Ke Cheng

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 250 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
250citing papers in PubMed, 4 pooled it
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

250 citing papers in PubMed, 4 syntheses or guidelines pooled it, 384 citations in OpenAlex.

  1. Pooled it
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  13. Extracellular vesicle-mediated mechanisms and therapeutic potential in acute lung injury.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
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190 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Adam VandergriffJoint Department of Biomedical Engineering at University of North Carolina at Chapel Hill and North Carolina State University.
Ke HuangDepartment of Molecular and Biomedical Sciences and Comparative Medicine Institute, North Carolina State University, Raleigh, North Carolina.
Deliang ShenDepartment of Cardiovascular Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Shiqi HuJoint Department of Biomedical Engineering at University of North Carolina at Chapel Hill and North Carolina State University.
Michael Taylor HensleyDepartment of Molecular and Biomedical Sciences and Comparative Medicine Institute, North Carolina State University, Raleigh, North Carolina.
Thomas G CaranasosDepartment of Cardiothoracic Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Li QianDepartment of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Ke ChengJoint Department of Biomedical Engineering at University of North Carolina at Chapel Hill and North Carolina State University.
University of North Carolina at Chapel Hill · USNorth Carolina State University · USFirst Affiliated Hospital of Zhengzhou University · CN

Funding

Targeted Nanoparticles for Stem Cell Redirecting and Regenerative MedicineR01HL123920 · NHLBI · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI CHENG, KE · 2015 to 2023
$4.8M
Enhancing vascular delivery of stem cells and microparticlesR01HL137093 · NHLBI · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI CHENG, KE · 2017 to 2020
$1.5M
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ExosomesAdministration, IntravenousAnimalsBiological ProductsBiological TherapyCell SurvivalDisease Models, AnimalEchocardiographyMolecular Targeted TherapyMyocardial InfarctionMyocytes, CardiacPeptidesRatsTreatment OutcomeBiological ProductsPeptidescardiac regenerationexosomesheart diseasemyocardial infarctionTargeting

Identifiers

PMID29556361
PMCPMC5858505
OpenAlexW2794260489

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.