Evidence map›Paper›PMID 29556341›Full record

ArticleTheranostics2018

Oxygen-generating Hybrid Polymeric Nanoparticles with Encapsulated Doxorubicin and Chlorin e6 for Trimodal Imaging-Guided Combined Chemo-Photodynamic Therapy.

DanRong Hu, LiJuan Chen, Ying Qu, JinRong Peng, BingYang Chu, Kun Shi, Ying Hao, Lin Zhong, MengYao Wang, ZhiYong Qian

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
13.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 210 citations in OpenAlex.

  1. Review
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  7. Unveiling the Antibacterial Efficacy and Mechanistic Insights of MnOInternational journal of molecular sciences · 2025
    Article
  8. Review
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  10. Article
  11. Review
  12. Article
  13. Review
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  16. 3D Bioprinting of Smart Oxygen-Releasing Cartilage Scaffolds.Journal of functional biomaterials · 2022
    Review
  17. Review
  18. Review
  19. Nanotechnology in drug and gene delivery.Naunyn-Schmiedeberg's archives of pharmacology · 2022
    Review
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

DanRong HuState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, and Collaborative Innovation Center. Chengdu 610041, PR China.
LiJuan ChenState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, and Collaborative Innovation Center. Chengdu 610041, PR China.
Ying QuState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, and Collaborative Innovation Center. Chengdu 610041, PR China.
JinRong PengState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, and Collaborative Innovation Center. Chengdu 610041, PR China.
BingYang ChuState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, and Collaborative Innovation Center. Chengdu 610041, PR China.
Kun ShiState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, and Collaborative Innovation Center. Chengdu 610041, PR China.
Ying HaoState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, and Collaborative Innovation Center. Chengdu 610041, PR China.
Lin ZhongState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, and Collaborative Innovation Center. Chengdu 610041, PR China.
MengYao WangState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, and Collaborative Innovation Center. Chengdu 610041, PR China.
ZhiYong QianState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, and Collaborative Innovation Center. Chengdu 610041, PR China.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The combination of chemotherapy with photodynamic therapy (PDT) has attracted broad attention as it can overcome limitations of conventional chemo-treatment by using different modes of action. However, the efficacy of PDT to treat solid tumors is severely affected by hypoxia in tumors.

Indexed as

AnimalsAntineoplastic AgentsBreast NeoplasmsCell Line, TumorChlorophyllidesCombined Modality TherapyDoxorubicinDrug CarriersDrug CompoundingFemaleHumansMagnetic Resonance ImagingManganese CompoundsMCF-7 CellsMiceMice, NudeAntineoplastic AgentsChlorophyllidesDoxorubicinDrug CarriersManganese Compoundsmanganese dioxideOxidesOxygenPhotosensitizing AgentsphytochlorinPolyesterspoly(ethylene glycol)-b-poly(lactide-co-epsilon-caprolactone)Polyethylene GlycolsPorphyrinscombination therapyhypoxia relievemanganese dioxide nanoparticlesMultifunctional nanoparticlesoxygen generationtheranostics

Identifiers

PMID29556341
PMCPMC5858167
OpenAlexW2794373765

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.