Evidence map›Paper›PMID 29556285›Full record

ArticleOncology letters2018

Overexpression of long non-coding RNA CRNDE facilitates epithelial-mesenchymal transition and correlates with poor prognosis in intrahepatic cholangiocarcinoma.

Xiu-Liang Xia, Dong Xue, Ting-Hai Xiang, Huai-Yong Xu, De-Kun Song, Pei-Guang Cheng, Jian-Qiang Wang

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Long Non-Coding RNAs as Molecular Biomarkers in Cholangiocarcinoma.Frontiers in cell and developmental biology · 2022
    Review
  6. Review
  7. Article
  8. Article
  9. Long non-coding RNA PRNCR1 has an oncogenic role in breast cancer.Experimental and therapeutic medicine · 2019
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. LncRNA-SNHG3 is an independent prognostic biomarker of intrahepatic cholangiocarcinoma.International journal of clinical and experimental pathology · 2019
    Article
  16. Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xiu-Liang XiaDepartment of General Surgery, The People's Hospital of Binzhou, Binzhou, Shandong 256610, P.R. China.
Dong XueDepartment of General Surgery, The People's Hospital of Binzhou, Binzhou, Shandong 256610, P.R. China.
Ting-Hai XiangDepartment of General Surgery, The People's Hospital of Binzhou, Binzhou, Shandong 256610, P.R. China.
Huai-Yong XuDepartment of General Surgery, The People's Hospital of Binzhou, Binzhou, Shandong 256610, P.R. China.
De-Kun SongDepartment of General Surgery, The People's Hospital of Binzhou, Binzhou, Shandong 256610, P.R. China.
Pei-Guang ChengDepartment of General Surgery, The People's Hospital of Binzhou, Binzhou, Shandong 256610, P.R. China.
Jian-Qiang WangDepartment of General Surgery, The People's Hospital of Binzhou, Binzhou, Shandong 256610, P.R. China.
Binzhou People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The clinical significance and essential role of long non-coding RNA colorectal neoplasia differentially expressed (lncRNA CRNDE) have been well illuminated in various cancers. However, the function of CRNDE in intrahepatic cholangiocarcinoma (IHCC) has not been reported at present. The aim of the present study was to investigate the role of CRNDE in IHCC. Firstly, the relative expression of CRNDE was observed to be upregulated in IHCC cell lines and tissues. And high CRNDE expression was statistically associated with IHCC differentiation grade, lymph node metastasis, tumor-nodes-metastasis (TNM) stage and size. Survival analysis identified that high CRNDE expression is a predictor of worse overall survival (OS) and progression-free survival (PFS) in patients with IHCC. Moreover, high CRNDE expression was identified as an independent risk factor of IHCC poor OS and PFS. Further studies of

Indexed as

EMTintrahepatic cholangiocarcinomalncRNA CRNDEmetastasisprognosisproliferation

Identifiers

PMID29556285
PMCPMC5844116
OpenAlexW2784566865

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.