Evidence map›Paper›PMID 29556175›Full record

ArticleFrontiers in neuroscience2018

Ventral Tegmental Area GABA Neurons Are Resistant to GABA(A) Receptor-Mediated Inhibition During Ethanol Withdrawal.

Ashley C Nelson, Stephanie B Williams, Stephanie S Pistorius, Hyun J Park, Taylor J Woodward, Andrew J Payne, J Daniel Obray, Samuel I Shin, Jennifer K Mabey, Scott C Steffensen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

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  10. Ethanol blocks a novel form of iLTD, but not iLTP of inhibitory inputs to VTA GABA neurons.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ashley C NelsonDepartment of Psychology and Center for Neuroscience, Brigham Young University, Provo, UT, United States.
Stephanie B WilliamsDepartment of Psychology and Center for Neuroscience, Brigham Young University, Provo, UT, United States.
Stephanie S PistoriusDepartment of Psychology and Center for Neuroscience, Brigham Young University, Provo, UT, United States.
Hyun J ParkDepartment of Psychology and Center for Neuroscience, Brigham Young University, Provo, UT, United States.
Taylor J WoodwardDepartment of Psychology and Center for Neuroscience, Brigham Young University, Provo, UT, United States.
Andrew J PayneDepartment of Psychology and Center for Neuroscience, Brigham Young University, Provo, UT, United States.
J Daniel ObrayDepartment of Psychology and Center for Neuroscience, Brigham Young University, Provo, UT, United States.
Samuel I ShinDepartment of Psychology and Center for Neuroscience, Brigham Young University, Provo, UT, United States.
Jennifer K MabeyDepartment of Psychology and Center for Neuroscience, Brigham Young University, Provo, UT, United States.
Scott C SteffensenDepartment of Psychology and Center for Neuroscience, Brigham Young University, Provo, UT, United States.
Brigham Young University · US

Funding

Nicotine and Alcohol Co-DependenceR01DA035958 · NIDA · BRIGHAM YOUNG UNIVERSITY · PI STEFFENSEN, SCOTT C · 2014 to 2018
$2.0M
Neuroplasticity with alcohol dependenceR01AA020919 · NIAAA · BRIGHAM YOUNG UNIVERSITY · PI STEFFENSEN, SCOTT C · 2012 to 2016
$1.5M
NIAAA NIH HHS R01 AA020919NIDA NIH HHS R01 DA035958
6 · The paper itself

Abstract

The neural mechanisms underlying alcohol dependence are not well-understood. GABAergic neurons in the ventral tegmental area (VTA) are a relevant target for ethanol. They are inhibited by ethanol at physiologically-relevant levels

Indexed as

alcoholGABAGABA(A) receptormuscimolneuronsVTAwithdrawal

Identifiers

PMID29556175
PMCPMC5844957
OpenAlexW2793350608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.