ArticleTexas Heart Institute journal2018
Effects of Older Donor Age and Cold Ischemic Time on Long-Term Outcomes of Heart Transplantation.
Article in Texas Heart Institute journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Donor heart selection: Evidence-based guidelines for providers.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2023Guideline
- Cardiac Graft Assessment in the Era of Machine Perfusion: Current and Future Biomarkers.Journal of the American Heart Association · 2021Pooled it
- Recent perioperative challenges in anesthesia during expansion of heart transplantation.Journal of cardiothoracic surgery · 2026Review
- Optimizing Temperature in Ex Situ Heart Perfusion: A Comparative Review of Traditional and Novel Methods in Heart Transplantation.Journal of cardiovascular development and disease · 2026Review
- Heart Transplantation.Journal of clinical medicine · 2024Review
- Donor Heart Preservation: Current Knowledge and the New Era of Machine Perfusion.International journal of molecular sciences · 2023Review
- Novel Imaging Technologies for Accurate Assessment of Cardiac Allograft Performance.Current transplantation reports · 2023Article
- Introduction of machine perfusion of donor hearts in a single center in Germany.International journal of cardiology. Heart & vasculature · 2023Article
- Autograft Aortic Root Replacement on Allograft During Heart Transplantation.Annals of thoracic surgery short reports · 2023Article
- Heart Transplantation With Older Donors: Should There Be an Age Cutoff?Transplantation proceedings · 2022Article
- Heart Transplant Donor Selection Guidelines: Review and Recommendations.Current cardiology reports · 2022Review
- Pathological Process of Prompt Connection between Host and Donor Tissue Vasculature Causing Rapid Perfusion of the Engineered Donor Tissue after Transplantation.International journal of molecular sciences · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Using older donor hearts in cardiac transplantation may lead to inferior outcomes: older donors have more comorbidities that reduce graft quality, including coronary artery disease, hypertension, diabetes mellitus, and dyslipidemia. Shorter cold ischemic times might overcome the detrimental effect of older donor age. We examined the relationship between donor allograft age and cold ischemic time on the long-term outcomes of heart transplant recipients. rom 1994 through 2010, surgeons at our hospital performed 745 heart transplantations. We retrospectively classified these cases by donor ages of <50 years (younger) and ≥50 years (older), then by cold ischemic times of <120 min (short), 120 to 240 min (intermediate), and >240 min (long). Endpoints included recipient and graft survival, and freedom from cardiac allograft vasculopathy, nonfatal major adverse cardiac events, and rejection. For intermediate ischemic times, the 5-year recipient survival rate was lower when donors were older (70% vs 82.6%;
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.