Evidence map›Paper›PMID 29556006›Full record

ArticleNature nanotechnology2018

Confinement-induced liquid crystalline transitions in amyloid fibril cholesteric tactoids.

Gustav Nyström, Mario Arcari, Raffaele Mezzenga

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature nanotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 151 citations in OpenAlex.

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  15. Solvent-Dependent Dynamics of Cellulose Nanocrystals in Process-Relevant Flow Fields.Langmuir : the ACS journal of surfaces and colloids · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gustav NyströmDepartment of Health Science and Technology, ETH Zurich, Zurich, Switzerland.ORCID 0000-0003-2739-3222
Mario ArcariDepartment of Health Science and Technology, ETH Zurich, Zurich, Switzerland.ORCID 0000-0002-9055-6525
Raffaele MezzengaDepartment of Health Science and Technology, ETH Zurich, Zurich, Switzerland. raffaele.mezzenga@hest.ethz.ch.ORCID 0000-0002-5739-2610
ETH Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chirality is ubiquitous in nature and plays crucial roles in biology, medicine, physics and materials science. Understanding and controlling chirality is therefore an important research challenge with broad implications. Unlike other chiral colloids, such as nanocellulose or filamentous viruses, amyloid fibrils form nematic phases but appear to miss their twisted form, the cholesteric or chiral nematic phases, despite a well-defined chirality at the single fibril level. Here we report the discovery of cholesteric phases in amyloids, using β-lactoglobulin fibrils shortened by shear stresses. The physical behaviour of these new cholesteric materials exhibits unprecedented structural complexity, with confinement-driven ordering transitions between at least three types of nematic and cholesteric tactoids. We use energy functional theory to rationalize these results and observe a chirality inversion from the left-handed amyloids to right-handed cholesteric droplets. These findings deepen our understanding of cholesteric phases, advancing their use in soft nanotechnology, nanomaterial templating and self-assembly.

Indexed as

AlgorithmsAmyloidCrystallizationLactoglobulinsLiquid CrystalsPhase TransitionStereoisomerismAmyloidLactoglobulins

Identifiers

PMID29556006
OpenAlexW2791555770

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.